在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Serpinh1 Antibody, HRP conjugated

  • 中文名稱:
    Serpinh1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA021087LB01MO
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Mus musculus (Mouse) Serpinh1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    Serpinh1
  • 別名:
    Serpinh1 antibody; Cbp1 antibody; Hsp47 antibody; Serpin H1 antibody; 47 kDa heat shock protein antibody; Collagen-binding protein antibody; Colligin antibody; Serine protease inhibitor J6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Mouse
  • 免疫原:
    Recombinant Mouse Serpin H1 protein (18-417AA)
  • 免疫原種屬:
    Mus musculus (Mouse)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
  • 基因功能參考文獻:
    1. The HSP47 might exert influence on liver fibrosis via the regulation ofendothelin receptor A (ETAR) and endothelin receptor B (ETBR). PMID: 28802097
    2. miR-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 expression. PMID: 27477081
    3. HSP47 appears after a period of certain activities to repair damaged collagen fibers, and the activity was returned to a state of equilibrium at day 30 with significantly diminished expression. Thus, the results suggest that HSP47 is actively involved in homeostasis of periodontal tissue subjected to occlusal overload PMID: 27076780
    4. Intradermal administration of siHSP47-nanoparticles effectively reduced HSP47 protein expression in skin to normal level. PMID: 26196532
    5. 2014). Data show that the expression of heat shock protein 47 (HSP47) was increased in the scleroderma mouse model. PMID: 26091621
    6. Deletion of Hsp47 caused activated hepatic stellate cells to undergo ER stress-mediated apoptosis when autophagy was inhibited PMID: 25525267
    7. Mouse embryonic stem cell migration and differentiation into smooth muscle cells is induced by the over-expression of HSP47. PMID: 24454956
    8. Authors conclude that heat shock protein 47 plays an essential role in Schistosoma japonicum-induced hepatic fibrosis in mice. PMID: 24295791
    9. miR-29b down-regulates HSP47 and LOX expression. PMID: 24650661
    10. expression patterns of HSP70 and HSP47 in tissues following short-pulse laser irradiation PMID: 23587755
    11. The pH sensitivity of murine heat shock protein 47 (HSP47) binding to collagen is affected by mutations in the breach histidine cluster. PMID: 23212911
    12. These results demonstrate that Hsp47 is indispensable for well-organized cartilage and normal endochondral bone formation. PMID: 22492985
    13. overexpression of HSP47 in keloid fibroblast cells could induce excessive collagen accumulation by enhancing collagen synthesis, which not only presents a possible mechanism of keloid formation PMID: 22295344
    14. alpha-smooth-muscle-actin-positive myofibroblast of bleomycin-induced pulmonary fibrosis cells may synthesize procollagen in the fibrotic process of bleomycin-treated lungs through upregulation of HSP47 mRNA and play an important role in fibrogenesis. PMID: 20094730
    15. HSP47 localized in alpha-smooth muscle actin-positive myofibroblasts, F4/80 negative, surfactant protein-A-positive type II pneumocytes, and F4/80-positive macrophages. Cells may play role in fibrotic process through upregulation of HSP47. PMID: 12842808
    16. Results indicate that Hsp47 is required for the molecular maturation of type IV collagen and suggest that misfolded type IV collagen causes abnormal morphology of embryoid bodies. PMID: 15282337
    17. type IV collagen in dilated endoplasmic reticulum leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP PMID: 15522896
    18. analysis of the client recognition mechanism of HSP47 PMID: 16326708
    19. analysis of recognition of the collagen triple helix by chaperone HSP47 PMID: 16484215
    20. Hsp47 is required for correct folding and prevention of aggregation of type I collagen in the ER. PMID: 16525016
    21. the HSP47-specific siRNA inhibited expression of HSP47 at the level of mRNA and protein, and furthermore, adenovirus-mediated transfer of siRNA against HSP47 inhibited the expression of type I collagen and formation of scar tissue in animal mod PMID: 18093850

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum lumen.
  • 蛋白家族:
    Serpin family
  • 數據庫鏈接:


主站蜘蛛池模板: 欧洲日韩亚洲无线在码| 国产乱码精品一区二区三区中文 | 护士人妻hd中文字幕| 无码av高潮抽搐流白浆| 久久99国产只有精品| 高潮爽死抽搐白浆gif视频| 无码av永久免费专区麻豆| 亚洲国产成人乱码| 亚洲色大18成人网站www在线播放| 无码中文字幕va精品影院| 精品国产一区二区三区免费| 中文字幕精品一二三四五六七八| 国产av国片精品| 国产欲女高潮正在播放| 2018年秋霞无码片| 久久精品人人做人人爽| 久久精品中文字幕无码 | 国产成 人 综合 亚洲网站| 亚洲中国最大av网站| 午夜人妻久久久久久久久| 国产精品亚洲专区无码web| 人人做人人爽久久久精品| 小13箩利洗澡无码视频网站| 搡老熟女老女人一区二区| 欧美xxxx做受欧美1314| 欧美成人午夜性视频| 99精品欧美一区二区三区| 最近免费中文字幕中文高清百度| 国产成人av片无码免费| 无码潮喷a片无码高潮视频| 无码av无码天堂资源网| 一本久久a久久免费精品不卡| 国产成人8x人网站在线视频| 风韵少妇性饥渴推油按摩视频| 成人免费视频在线观看| 无码av中文一区二区三区| 国产精品一区二区无线| 久久精品夜色噜噜亚洲a∨| 巨熟乳波霸若妻在线播放| 一道本在线伊人蕉无码| 50岁退休熟女露脸高潮|