在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SYTL4 Antibody

  • 中文名稱:
    SYTL4兔多克隆抗體
  • 貨號:
    CSB-PA780689
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from 3T3 cells, using SYTL4 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SYTL4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SYTL4
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from internal of Human SYTL4.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
  • 基因功能參考文獻:
    1. Determined the solution structure of human synaptotagmin-like protein 4 (Slp4). Through modification of cysteine residues, found Slp4 binding of two zinc atoms is required for correct folding. PMID: 28906046
    2. Granuphilin makes granules immobile and fusion-reluctant beneath the plasma membrane. Those granuphilin-positive, docked granules release a portion of granuphilin upon fusion, and fuse at a frequency and time course similar to those of granuphilin-negative undocked granules. Granuphilin forms a 180-nm cluster at the site of each docked granule, along with granuphilin-interacting Rab27a and Munc18-1 clusters. PMID: 27032672
    3. GLUT5 required an interaction cascade of Rab11, Myo5B, Slp4a, Munc18-2, and Vamp7 with Stx3. PMID: 26553929
    4. Phosphatidylinositol 4,5-bisphosphate binds to the concave surface of granuphilin-C2A domain. The key residues involved in the binding were validated by mutation analysis. PMID: 25595293
    5. the mechanisms of granuphilin plasma membrane targeting and release PMID: 24184645
    6. Recruitment of STXBP1 by the Rab27A effector SYTL4 promotes Weibel-Palade body exocytosis. PMID: 24700782
    7. Slp4 and Rab8 are expressed and interact in human platelets, and might be involved in dense granule release. PMID: 23140275
    8. in insulin-producing cells adequate levels of mir-9 are mandatory for maintaining appropriate Granuphilin levels and optimal secretory capacity PMID: 16831872
    9. Synaptotagmin-like protein 4 (Slp4)/granuphilin-a contains an N-terminal Slp homology domain (SHD) (PMID: 11327731). The SHD of Slp4 specifically and directly binds the GTP-bound form of Rab3A, Rab8, and Rab27A. PMID: 11773082

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein.
  • 數據庫鏈接:

    HGNC: 15588

    OMIM: 300723

    KEGG: hsa:94121

    STRING: 9606.ENSP00000263033

    UniGene: Hs.592224



主站蜘蛛池模板: 久久久橹橹橹久久久久| 国产美女自卫慰水免费视频 | 久久精品国产日本波多野结衣| 四虎免费大片aⅴ入口| 国产精品无码mv在线观看| 久久婷婷丁香七月色综合| 欧美成aⅴ人高清ww| 76少妇精品导航| 理论片87福利理论电影| 黄页网站在线观看免费视频| 国产中的精品av一区二区| 一本久久知道综合久久| 国产在线aaa片一区二区99| 182tv午夜福利在线地址二| 欧美老肥妇多毛xxxxx| 色噜噜狠狠狠狠色综合久| 色婷婷综合久久久久中文字幕| 亚洲精品你懂的在线观看| 免费视频爱爱太爽了网站| 无码人妻精品中文字幕免费东京热| 国产亚洲美女精品久久久| 国产一区二区三区精品av| 国产精品线路一线路二| 亚洲精品国产suv一区88| 亚洲精品一区二区三区四区五区| 亚洲精品熟女国产| 亚洲精品一线二线三线区别大吗| 中文字幕一区在线观看视频| 国产麻豆md传媒视频| 久久国产成人免费网站777| 国产精品天干在线观看| 色噜噜狠狠狠综合曰曰曰| 久久99精品国产99久久6尤物| 国产人成高清在线视频99最全资源 | 一本大道熟女人妻中文字幕在线| 国产成人免费爽爽爽视频| 亚洲精品成人网站在线播放| 亚洲愉拍二区一区三区| 精品久久久久久久久久中文字幕| 精品第一国产综合精品蜜芽| 亚洲国产精品久久久久秋霞小|