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  4. SYT6 Antibody

SYT6 Antibody

  • 中文名稱：
    SYT6兔多克隆抗體
  • 貨號：
    CSB-PA716356LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA716356LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SYT6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SYT6
  • 別名：
    Synaptotagmin 6 antibody; Synaptotagmin VI antibody; Synaptotagmin-6 antibody; Synaptotagmin6 antibody; SynaptotagminVI antibody; Syt 6 antibody; Syt VI antibody; SYT6 antibody; SYT6_HUMAN antibody; SytVI antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Synaptotagmin-6 protein (104-425AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SYT6 Antibody (CSB-PA716356LA01HU)，的標記方式是Non-conjugated。對于SYT6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA716356LB01HU SYT6 Antibody, HRP conjugated ELISA
    FITC CSB-PA716356LC01HU SYT6 Antibody, FITC conjugated
    Biotin CSB-PA716356LD01HU SYT6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.
  • 基因功能參考文獻：
    1. synaptotagmin must be dephosphorylated at a specific window of time and phosphorylated synaptotagmin has an active role at early stages of the acrosomal exocytosis. PMID: 20551332
    2. Acrosomal exocytosis is regulated through the PKC-mediated phosphorylation of conserved threonines in the polybasic regions of synaptotagmin VI. PMID: 16111671
    3. SYT6 is hypermethylated in renal cell carcinoma. PMID: 18639284
  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.; [Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    Synaptotagmin family
  • 數據庫鏈接：

    HGNC: 18638

    OMIM: 607718

    KEGG: hsa:148281

    STRING: 9606.ENSP00000358559

    UniGene: Hs.370963



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