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Your Good Partner in Biology Research

SYT5 Antibody

  • 中文名稱:
    SYT5兔多克隆抗體
  • 貨號:
    CSB-PA074430
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA074430(SYT5 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA074430(SYT5 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human thigh malignant fibrous histiocytoma tissue, Primary antibody: CSB-PA074430(SYT5 Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 8 hours
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SYT5
  • 別名:
    SYT5; Synaptotagmin-5; Synaptotagmin V; SytV
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human SYT5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
  • 基因功能參考文獻:
    1. Ca(2+)-binding pocket of synaptotagmin 5 C2A domain PMID: 27793683
    2. crystals of synaptotagmin 5 belonged to the hexagonal space group P6(5), with unit-cell parameters a = b = 93.97, c = 28.05 A. PMID: 22102235
    3. results suggest a novel putative functional role for the GST-synaptotagmin V complex in human breast cancers. As this association of GST M1-synaptotagmin was not seen in adjacent non-cancerous tissues, this can be used as a marker for breast cancers. PMID: 15820774
  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein.
  • 蛋白家族:
    Synaptotagmin family
  • 數據庫鏈接:

    HGNC: 11513

    OMIM: 600782

    KEGG: hsa:6861

    STRING: 9606.ENSP00000346265

    UniGene: Hs.631566



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