在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

STS Antibody

  • 中文名稱:
    STS兔多克隆抗體
  • 貨號(hào):
    CSB-PA022883GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    STS
  • 別名:
    STS; ARSC1; Steryl-sulfatase; Arylsulfatase C; ASC; Estrone sulfatase; Steroid sulfatase; Steryl-sulfate sulfohydrolase
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human STS
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid.
  • 基因功能參考文獻(xiàn):
    1. Polymorphisms of STS gene is associated with attention-deficit/hyperactivity disorder. PMID: 28367959
    2. STS is increased in preeclamptic placentas and maternal whole blood. Our data suggests that STS may affect sFlt1 secretion by regulating sFlt1-i13 transcription, and not via alterations in syncytialisation. PMID: 27871476
    3. This study reveals that STS is a key player of steroid biosynthesis regulating the availability of circulating cholesterol. PMID: 27531568
    4. In contrast to the situation in boys with ADHD, in healthy men, the G-allele at rs17268988 of STS is associated with enhanced cognition. PMID: 28293481
    5. miR-661 overexpression sensitized tumors to TRAIL or STS induced apoptosis in a xenograft mouse model, and these effects were attenuated by co-expression of CYC1. PMID: 28391262
    6. Collectively, STS point mutations demonstrate restricted localization, causing efficient impairment of the corresponding enzyme activity, and are more unlikely to be responsible for the phenotypic heterogeneity in XLRI subjects PMID: 26387488
    7. STS expression was not significantly associated with DFS and OS, despite positive STS expression in 27% of endometrial cancer patients. Therefore, the role of STS as a prognostic factor in patients with endometrial cancer remains unclear and requires further research. PMID: 26996578
    8. The induced STS facilitates the conversion of inactive estrogen sulfates to active estrogens, which in return attenuates the NF-kappaB-mediated inflammation. PMID: 26220752
    9. The antagonistic actions of glucocorticoids and NFkB on STS expression are similar to the regulation of inflammatory response proteins PMID: 26631368
    10. Letter/Case Report: novel nonsense mutation in the STS gene in X-linked ichthyosis. PMID: 26421812
    11. Data show that both estrogen sulfatase (STS) and estrogen sulfotransferase (EST) were highly expressed in the human umbilical vein endothelial cells (HUVECs). PMID: 26458420
    12. Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells PMID: 26723541
    13. represents one of the major pathways in regenerating biologically active steroids in both steroidogenic and nonsteroidogenic tissues [review] PMID: 26213785
    14. Our analyses show that the two phenotypes in our patient are due to independent genetic defects: a genomic rearrangement involving the Kallmann syndrome 1 gene and a point mutation of the steryl-sulfatase gene. PMID: 25726327
    15. In both arm and subumbilical skin biopsy of patients with idiopathic hirsutism, there was an up-regulation of STS mRNA expression. PMID: 26194504
    16. Genetic variation in ARSC may be associated with change in mammographic density after women stop using estrogen-progestin therapy. PMID: 25499601
    17. STS is present in human pre-osteoblastic bone cells and that it can influence bone cell growth PMID: 25042472
    18. complete deletion in Pakistani families with x-linked ichthyosis PMID: 24480088
    19. results suggest that steroid sulfatase expression can be decreased in the process of large intestinal carcinogenesis PMID: 23916543
    20. Data suggest that expression of STS and 17beta-hydroxysteroid dehydrogenase isoenzymes is up-regulated in subcutaneous abdominal fat of morbidly obese women as compared with morbidly obese men. PMID: 24081738
    21. Microdeletion within Xp22.3 containing STS with aCGH in an individual with suspected pre-Descemet corneal dystrophy and X-linked ichthyosis demonstrates the clinical utility of copy number variation analysis. PMID: 23807007
    22. IGF-II induces steroid sulfatase expression via a PI3-kinase/Akt-NF-kappaB signaling pathway in PC-3 cells and may induce estrogen production and estrogen-mediated carcinogenesis. PMID: 24055520
    23. Genetic variants in SULT2A1, PAPSS2, and STS do not predispose to polycystic ovary syndrome. PMID: 23861462
    24. no difference in placental activity found between women with polycystic ovarian syndrome and controls PMID: 23122578
    25. Genetic variants affecting steroid sulfatase expression and/or activity could influence the function of brain regions perturbed in attention deficit hyperactivity disorder (ADHD). PMID: 21255266
    26. Filaggrin defects can synergize with steroid sulfatase deficiency to exacerbate the ichthyosis phenotype. PMID: 21945601
    27. Recent results of STS and EST in several estrogen-dependent carcinomas, are summarised. PMID: 21073915
    28. This timely review concentrates on recent advances in steroid sulfatase research. PMID: 21693170
    29. Case Report: Report novel point mutation in the STS gene in a patient with X-linked recessive ichthyosis. PMID: 21530180
    30. Genetic variation in the STS gene may be implicated in ADHD susceptibility and one polymorphism may be associated with lower STS mRNA expression as well as being more prevalent in female ADHD homozygotes. PMID: 20862695
    31. Recessive X-linked ichthyosis is caused by a deficiency in steroid sulphatase (STS), whose gene has been located on the X chromosome. PMID: 20236202
    32. Six novel single nucleotide polymorphisms of the steroid sulfatase gene in a Japanese population. PMID: 20814163
    33. A significant increment of STS followed exemestane neoadjuvant therapy of postmenopausal ER-positive breast carcinoma. This may represent the compensatory response of breast carcinoma tissues to estrogen depletion. PMID: 20151319
    34. Both steroid sulfatase and filaggrin mutations are found in X-linked ichthyosis. PMID: 20149601
    35. Analysis of deletions indicates complex origin, apart from homologous recombination, of deletion mutants. PMID: 11844872
    36. in the human hair follicle, concentrates in the dermal papilla. PMID: 11886493
    37. Regulation of estrogen activity in human endometrium: effect of IL-1beta on steroid sulfatase activity in human endometrial stromal cells. PMID: 11996939
    38. data demonstrate that LNCaP prostate cancer cells contain a steryl sulfatase with properties similar to that found in human breast cancer cells PMID: 12231117
    39. The structure of this enzyme, purified from the microsomal fraction of human placentas, determined by x-ray crystallography. PMID: 12657638
    40. Levels of STS and estrogen sulfotransferase mRNA and activity may be significantly associated with degree of atherosclerotic changes in female aorta, which may be related to cytokines produced in situ, such as IL-1beta, in human atherosclerotic lesions. PMID: 14507642
    41. estrogen-dependent cell growth of the estrogen sulfatase-transfected cell clones was found to be abolished, due to the enhanced sulfoconjugation of estrogen PMID: 14556660
    42. Steroid sulfatase increases steroid acute regulatory protein expression level and stimulates steroid production. PMID: 14969586
    43. SSase is concentrated in lamellar bodies (LB), and secreted into the SC interstices, along with other LB-derived lipid hydrolases. There, it degrades CSO4, generating some cholesterol for the barrier PMID: 15009711
    44. Strong activity and mRNA expression of DHEAS desulfating STS was found, twice as high in cerebral neocortex than in subcortical white matter. Cerebral STS resembled the characteristics of the known placental enzyme PMID: 15056284
    45. Dehydroepiandrosterone blood levels are influenced by a steroid sulfatase polymorphism following acute resistance exercise. PMID: 15152080
    46. Gonadotropin-releasing hormone agonist (leuprolide)inhibits estrone sulfatase expression in cystic endometriosis in the ovary. PMID: 15302278
    47. Increased steroid sulfatase expression is associated with estrogen-dependent endometrial carcinomas PMID: 15355916
    48. Findings of steroid sulfatase localized in the cytoplasm of the cumulus cells and expression of STS mRNA suggest a local steroidal regulation mechanism in cumulus cells. PMID: 16084891
    49. Studies on the localization of steroid sulfatase were performed. PMID: 16399357
    50. Corticotrophin-releasing hormone (CRH) increased whereas alpha-helical CRH decreased the mRNA levels of STS, CYP19A1, and HSD17B1, the key enzymes for estrogen synthesis. PMID: 16467490

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Ichthyosis, X-linked (IXL)
  • 亞細(xì)胞定位:
    Cytoplasmic vesicle, secretory vesicle, microneme membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Sulfatase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11425

    OMIM: 300747

    KEGG: hsa:412

    STRING: 9606.ENSP00000217961

    UniGene: Hs.522578



主站蜘蛛池模板: 国产精品18久久久久久欧美| 97久久精品无码一区二区| 色悠久久久久综合网香蕉| 曰韩精品无码一区二区视频| 国产精品亚洲一区二区z| 东京无码熟妇人妻av在线网址| 手机看片福利一区二区三区| av狼友无码国产在线观看| 成人无码精品免费视频在线观看| 人妻在卧室被老板疯狂进入| 国产在线观看码高清视频| 免费看又黄又爽又猛的视频软件| 中国凸偷窥xxxx自由视频| 内射人妻少妇无码一本一道| 亚洲日韩v无码中文字幕| 亚洲中文字幕乱码av波多ji| 日本熟妇色xxxxx欧美老妇| 啪啪无码人妻丰满熟妇| 成人影片麻豆国产影片免费观看| 国产av老师丝袜美腿丝袜| 亚洲 欧美 中文 日韩aⅴ| av小次郎收藏| 亚洲精品www久久久久久| 精品国精品国产自在久国产不卡| 欧美黑人巨大xxxxx视频| 5d肉蒲团之性战奶水| 国产免费丝袜调教视频| 亚洲欧美日韩视频高清专区| 国产日产欧产美韩系列影片| 2024av天堂手机在线观看| 亚洲国产欧美在线成人| 国产高清精品软件丝瓜软件| 中文字幕无线码中文字幕免费| 久久国产成人精品国产成人亚洲| 麻豆果冻国产剧情av在线播放| 国产精品欧美久久久久无广告 | 人体内射精一区二区三区| 国产成人无码18禁午夜福利p| 2021国产精品视频网站| 蜜桃少妇av久久久久久久| 99精品视频九九精品视频|