在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STK36 Antibody

STK36 Antibody

  • 中文名稱：
    STK36兔多克隆抗體
  • 貨號：
    CSB-PA008863
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    STK36
  • 別名：
    FU antibody; Fused homolog antibody; KIAA1278 antibody; Serine/threonine kinase 36, fused homolog antibody; Serine/threonine protein kinase 36 fused homolog antibody; Serine/threonine-protein kinase 36 antibody; STK36 antibody; STK36_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human STK36.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.
  • 基因功能參考文獻：
    1. Data identified homozygous loss-of-function mutations in STK36 in one PCD-affected individual with situs solitus. Transmission electron microscopy analysis demonstrates that STK36 is required for cilia orientation in human respiratory epithelial cells, with a probable localization of STK36 between the RS and CP. STK36 screening can now be included for this rare and difficult to diagnose PCD subgroup. PMID: 28543983
    2. Fu ubiquitination and cleavage is one of the key elements connecting the MID1-PP2A protein complex with GLI3 activity control PMID: 25278022
    3. The FU gene and its genomic structure was identified. PMID: 15268766
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性：
    Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis, where it is localized in germ cells.
  • 數據庫鏈接：

    HGNC: 17209

    OMIM: 607652

    KEGG: hsa:27148

    STRING: 9606.ENSP00000295709

    UniGene: Hs.471404



主站蜘蛛池模板： 天天干天天射天天操| 国产手机在线无码播放视频| 粗大猛烈进出高潮视频| 熟妇高潮喷沈阳45熟妇高潮喷| 人妻体内射精一区二区| 日韩精品乱码av一区二区| 精品久久久久久777米琪桃花| 亚洲午夜未满十八勿入| 国产精品宾馆在线精品酒店| 99re热视频这里只精品| 伊人久久精品在热线热| 欧美变态另类牲交| 国产办公室秘书无码精品99| 亚洲高清最新av网站| 无码专区3d动漫精品免费| 曰韩精品无码一区二区视频| 国产成人国产在线观看| 国产高清在线精品一区| 九九精品成人免费国产片| 2021少妇久久久久久久久久| 欧美乱大交xxxxx疯狂俱乐部| 亚洲欧美中文日韩在线v日本| 亚洲色在线v中文字幕| 亚洲精品久久66国产高清| 精品亚洲国产成人av在线小说| 欧美肉大捧一进一出免费视频| 免费观看激色视频网站| 小说区亚洲综合第1页| 亚洲一本一道一区二区三区| 美丽的熟妇中文字幕| 国自产拍偷拍精品啪啪模特| 久久久噜噜噜久久熟女色| 伊人久久大香线蕉无码| 夜爽8888视频在线观看| 色欲αv一区二区三区天美传媒| 亚洲日本乱码一区二区产线一∨| 成熟女人牲交片免费观看视频| 亚洲一线二线三线写真| 日本成本人三级在线观看| 巨大欧美黑人xxxxbbbb| 亚洲精品久久7777777|