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STK17A Antibody

  • 中文名稱:
    STK17A兔多克隆抗體
  • 貨號:
    CSB-PA204025
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA204025(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA204025(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    STK17A
  • 別名:
    DAP kinase-related apoptosis-inducing protein kinase 1 antibody; death-associated protein kinase-related 1 antibody; DRAK1 antibody; EC 2.7.11.1 antibody; Serine / threonine kinase 17a death associated protein kinase related 1 antibody; Serine/threonine kinase 17a antibody; Serine/threonine protein kinase 17a antibody; Serine/threonine-protein kinase 17A antibody; ST17A_HUMAN antibody; STK17 A antibody; STK17A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human STK17A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
  • 基因功能參考文獻:
    1. These findings suggest that DRAK1 translocates in response to stimuli and induces apoptosis through its interaction with specific binding partners, p53 and/or ANT2. PMID: 29397938
    2. the present study was the first to find localization of STK17A in normal bile canaliculi. PMID: 26305096
    3. DRAK1 was predominantly localized in the cytoplasm and bound to Smad3, thereby interrupting Smad3/Smad4 complex formation, which is the core process for the induction of tumor suppressor genes by TGF-beta1 PMID: 25531329
    4. STK17A provides a proliferative and survival advantage to GBM cells PMID: 24312360
    5. When analyzing STK17A haplotypes distribution, we found association between TGGTC, TAGTC and AAGAT haplotypes and risk to develop SLE PMID: 23860322
    6. identified STK17A as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. PMID: 21489989

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  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
  • 組織特異性:
    Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
  • 數據庫鏈接:

    HGNC: 11395

    OMIM: 604726

    KEGG: hsa:9263

    STRING: 9606.ENSP00000319192

    UniGene: Hs.709489



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