在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

STK10 Antibody

  • 中文名稱:
    STK10兔多克隆抗體
  • 貨號:
    CSB-PA022832GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    STK10
  • 別名:
    LOK antibody; Lymphocyte oriented kinase antibody; Lymphocyte-oriented kinase antibody; PRO2729 antibody; Serine threonine protein kinase 10 antibody; Serine/threonine-protein kinase 10 antibody; STK10 antibody; STK10_HUMAN antibody
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Human STK10
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.
  • 基因功能參考文獻:
    1. Binding of phosphatidylinositol 4,5-biphosphate to ezrin induces a conformational change permitting the insertion of the LOK C-terminal domain to wedge apart the membrane and F-actin-binding domains of ezrin. The N-terminal LOK kinase domain can then access a site 40 residues distal from the consensus sequence that collectively direct phosphorylation of the appropriate threonine residue. PMID: 28430576
    2. The gene signature of OPA1, CTSA, NDUFA1, STK10 and PRDX1 was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls. PMID: 27177495
    3. STK10 functions as a tumor suppressor gene, and dysfunction of STK10 activity either through polymorphism or somatic mutations may confer anti-apoptotic effects contributing to carcinogenesis. PMID: 23842845
    4. It was shown that lymphocyte-oriented and STE20 kinase were sufficient to restrict ezrin function to the apical domain. Both kinases were enriched in microvilli and locally activated there. PMID: 23209304
    5. genetic polymorphism is associated with aspirin-intolerant asthma in a Korean population PMID: 21905501
    6. Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells PMID: 11903060
    7. Stk10 is a novel polo-like kinase kinase that cooperates with hSlk to regulate Plk1 function in human cells PMID: 12639966
    8. These studies identify a new ERM kinase of importance in lymphocytes and confirm the role of ezrin-radixin-moesin phosphorylation in regulating cell shape and motility. PMID: 19255442

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Testicular germ cell tumor (TGCT)
  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein.
  • 蛋白家族:
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  • 組織特異性:
    Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung.
  • 數據庫鏈接:

    HGNC: 11388

    OMIM: 273300

    KEGG: hsa:6793

    STRING: 9606.ENSP00000176763

    UniGene: Hs.744005



主站蜘蛛池模板: 成人免费看片又大又黄| 在线中文字幕亚洲日韩2020| 真实国产乱啪福利露脸| 婷婷四房色播| 伊人精品一本久久综合| 热re99久久6国产精品免费| 天天干天天日夜夜操| 日本乱妇乱子视频网站-百度| 中无码人妻丰满熟妇啪啪| 无码一卡二卡三卡四卡| 成人影院yy111111在线观看| а√资源新版在线天堂| 久久婷婷五月综合色首页| 国产成人夜色高潮福利影视| 精品1卡二卡三卡四卡老狼| 久久久精品国产sm调教网站| 亚洲国产精品一区二区动图| 巨爆乳中文字幕巨爆区巨爆乳无码 | 亚洲中文字幕无码中字| 成人3d动漫一区二区三区| 亚洲成av人无码中文字幕| 国产精品久久久爽爽爽麻豆色哟哟| 欧美激情第1页| 久久精品66免费99精品| 亚洲热妇无码av在线播放| 精品人妻系列无码人妻漫画| 国产精品久久久久av| 亚洲成a人片在线观看天堂| 无码超乳爆乳中文字幕| 永久免费无码日韩视频| 免费人成在线观看视频无码| 精品久久久无码人妻中文字幕豆芽| 曰曰摸夜夜添夜夜添高潮出水| 亚洲欧洲av无码专区| 亚洲日本乱码一区二区产线一∨| 国产免费无码一区二区三区| 国产欧美日韩专区发布| 国产精品亚洲综合色区| 真人无码作爱免费视频| 少妇与黑人一二三区无码| 亚洲综合无码av一区二区三区 |