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ST6GALNAC1 Antibody

  • 中文名稱:
    ST6GALNAC1兔多克隆抗體
  • 貨號:
    CSB-PA022761GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ST6GALNAC1
  • 別名:
    6-sialyltransferase 1 antibody; 6-sialyltransferase I antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase antibody; Alpha-N-acetylgalactosaminide alpha-2 antibody; GalNAc alpha 2 6 sialyltransferase I antibody; GalNAc alpha-2 antibody; HSY11339 antibody; SIA7A_HUMAN antibody; Sialyltransferase 7A antibody; SIAT7-A antibody; SIAT7A antibody; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; ST6GalNAc I antibody; ST6GALNAC1 antibody; ST6GalNAcI antibody; STYI antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ST6GALNAC1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻(xiàn):
    1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma PMID: 28035351
    2. ST6GalNAc I regulates the gene expression of IGF-1 through STAT5b activation and plays role in gastric cancer invasion and metastasis. PMID: 25532910
    3. upregulated Siat7A expression, which was paralleled by the increased Klf4 in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction PMID: 25860962
    4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells. PMID: 24840470
    5. It was confirmed that MUC1 carries sialyl Tn also in human advanced gastric cancer tissues PMID: 22228572
    6. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn antigen at the cell surface. PMID: 12820722
    7. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer PMID: 16319059
    8. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis. PMID: 19287074

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  • 亞細(xì)胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 29 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 23614

    OMIM: 610138

    KEGG: hsa:55808

    STRING: 9606.ENSP00000156626

    UniGene: Hs.105352



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