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ST3GAL3 Antibody

  • 中文名稱：
    ST3GAL3兔多克隆抗體
  • 貨號：
    CSB-PA606136LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: ST3GAL3 antibody at 2µg/ml + Mouse skeletal muscle tissue
      Secondary
      Goat polyclonal to rabbit lgG at 1/15000 dilution
      Predicted band size: 43, 44, 20, 50, 39, 22, 32, 13, 21, 14, 18, 49, 17, 41, 31, 16, 47, 26, 27, 12, 23, 6, 9 kDa
      Observed band size: 43 kDa
  • 其他：

產品詳情

  • 產品描述：

    The peptide corresponding to amino acid residues 29-375 of the human ST3GAL3 protein is used to immunize rabbits to produce the ST3GAL3 antibody. This resulting antibody is a polyclonal antibody and occurs as an unconjugated IgG. Its purity is 95%+ using protein G purified. It can cross-react with human and mouse ST3GAL3 protein. And it is available for use in ELISA and WB applications. The target protein ST3GAL3 is a type II membrane protein responsible for catalyzing the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. It is involved in the pathogenesis of mental retardation, autosomal recessive 12 (MRT12) and epileptic encephalopathy, early infantile, 15 (EIEE15).

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ST3GAL3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ST3GAL3
  • 別名：
    3 sialyltransferase antibody; 3(4) GlcNAc alpha-2 antibody; 3-sialyltransferase 3 antibody; 3-sialyltransferase antibody; 3-ST 3 antibody; 4-galactoside alpha-2 antibody; 4GlcNAc alpha 2 3 sialyltransferase antibody; Alpha 2 3 sialyltransferase II antibody; Alpha 2 3 sialyltransferase III antibody; Alpha 2 3 ST 3 antibody; Alpha 2 antibody; Beta galactoside alpha 3 sialyltransferase 3 antibody; Beta-galactoside alpha-2 antibody; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase antibody; CMP-N-acetylneuraminate-beta-1 antibody; EC 2.4.99.6 antibody; Gal beta 1 3 antibody; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta-1 antibody; N acetyllactosaminide alpha 2 3 sialyltransferase antibody; N-acetyllactosaminide alpha-2 antibody; OTTHUMP00000008820 antibody; OTTHUMP00000008821 antibody; OTTHUMP00000008822 antibody; OTTHUMP00000008823 antibody; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase) antibody; Sialyltransferase 6 antibody; SIAT6 antibody; SIAT6_HUMAN antibody; ST3 beta galactoside alpha 2 3 sialyltransferase 3 antibody; ST3 beta galactoside alpha 2,3 sialyltransferase 3 antibody; ST3Gal III antibody; St3gal3 antibody; ST3GALII antibody; ST3GalIII antibody; ST3N antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase protein (29-375AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ST3GAL3 Antibody (CSB-PA606136LA01HU)，的標記方式是Non-conjugated。對于ST3GAL3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA606136LB01HU ST3GAL3 Antibody, HRP conjugated ELISA
    FITC CSB-PA606136LC01HU ST3GAL3 Antibody, FITC conjugated
    Biotin CSB-PA606136LD01HU ST3GAL3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
  • 基因功能參考文獻：
    1. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3. PMID: 27535614
    2. ST3Gal3 knockdown synergistically enhanced cisplatin-induced apoptosis in ovarian cancer cells PMID: 27871859
    3. ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules. PMID: 27779707
    4. Dysfunctional ST3GAL3 may result in perturbation of the posttranslational sialylation of proteins in these pathways PMID: 23252400
    5. ST3GAL3 mutations impair the development of higher cognitive functions. PMID: 21907012
    6. Characterization of the promoter region of the ST3Gal III gene. PMID: 12697334
    7. 19 different transcripts of ST3GalIII were isolated and cloned; tissue distribution analysis showed complex patterns in neural and muscular tissues PMID: 12815231
    8. High levels of ST3GAL-III in the tumor tissue correlated with secondary local tumor recurrence (p = 0.005; p = 0.012). PMID: 12931020
    9. Identification of a new ST3Gal3 transcript from fetal brain. PMID: 15316282

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  • 相關疾病：
    Mental retardation, autosomal recessive 12 (MRT12); Epileptic encephalopathy, early infantile, 15 (EIEE15)
  • 亞細胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 組織特異性：
    Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
  • 數據庫鏈接：

    HGNC: 10866

    OMIM: 606494

    KEGG: hsa:6487

    UniGene: Hs.597915



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