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  4. SSC1 Antibody

SSC1 Antibody

Rare Species
  • 中文名稱：
    SSC1兔多克隆抗體
  • 貨號：
    CSB-PA206965XA01SVG
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: SSC1 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35.4 kDa
      Observed band size: 40 kDa
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SSC1
  • 別名：
    Heat shock protein SSC1, mitochondrial (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70) SSC1 ENS1 YJR045C J1639
  • 反應種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSC1 protein (363-654aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Protein G
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed frataxin homolog YFH1 into the mitochondrion.
  • 基因功能參考文獻：
    1. Amino acid substitution within SSC1 reveals structural elements within mtHsp70s that are required for allosteric modulation of the chaperone cycle. PMID: 24829379
    2. Results show that mtHsp70-Cox4 complex likely serves as a novel delivery system to channel Cox4 into the assembly line when needed. PMID: 23864706
    3. The intrinsic dynamics of the substrate-binding domain of Ssc1 was observed to be uncoupled from the dynamic interactions between substrate- and nucleotide-binding domains. PMID: 23624933
    4. the critical amino acid sequence of Ssc1 and Ssc3 that can "make or break" mtHsp70 chaperone function. PMID: 21474445
    5. interactions between Tim44 and mtHsp70, controlled by polypeptide binding, are required for efficient translocation across the mitochondrial inner membrane PMID: 15489862
    6. The N-terminal 167-amino-acid segment of mature Tim44 is sufficient for both interaction with mtHsp70 and destabilization of a Tim44-mtHsp70 complex caused by client protein binding. PMID: 18426906

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  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Heat shock protein 70 family
  • 數據庫鏈接：

    KEGG: sce:YJR045C

    STRING: 4932.YJR045C



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