在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SRSF10 Antibody

SRSF10 Antibody

  • 中文名稱：
    SRSF10兔多克隆抗體
  • 貨號(hào)：
    CSB-PA525638LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA525638LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SRSF10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    40 kDa SR repressor protein antibody; 40 kDa SR-repressor protein antibody; Anti TLS associated protein with SR repeats antibody; arginine/serine-rich 13A antibody; FUS interacting protein serine arginine rich 1 antibody; FUS interacting protein serine arginine rich 2 antibody; FUS interacting serine arginine rich protein 1 antibody; FUS-interacting serine-arginine-rich protein 1 antibody; FUSIP1 antibody; FUSIP2 antibody; NSSR antibody; OTTHUMP00000015774 antibody; Serine arginine repressor protein 40 kDa antibody; Serine/arginine-rich splicing factor 10 antibody; SFRS13 antibody; SFRS13A antibody; Splicing factor antibody; Splicing factor arginine serine rich 13 antibody; Splicing factor SRp38 antibody; SRp38 antibody; SRp40 antibody; SRrp40 antibody; SRS10_HUMAN antibody; Srsf10 antibody; TASR antibody; TASR1 antibody; TASR2 antibody; TLS associated protein TASR1 antibody; TLS associated protein TASR2 antibody; TLS associated protein with Ser Arg repeats antibody; TLS associated protein with SR repeats antibody; TLS associated serine arginine protein 1 antibody; TLS associated serine arginine protein 2 antibody; TLS associated serine arginine protein antibody; TLS associated SR protein antibody; TLS-associated protein with Ser-Arg repeats antibody; TLS-associated protein with SR repeats antibody; TLS-associated serine-arginine protein antibody; TLS-associated SR protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/arginine-rich splicing factor 10 protein (1-183AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，SRSF10 Antibody (CSB-PA525638LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SRSF10 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA525638LB01HU SRSF10 Antibody, HRP conjugated ELISA
    FITC CSB-PA525638LC01HU SRSF10 Antibody, FITC conjugated
    Biotin CSB-PA525638LD01HU SRSF10 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator.
  • 基因功能參考文獻(xiàn)：
    1. DNA damage co-opts SRSF10 to control splicing decisions in transcripts encoding components involved in DNA repair, cell-cycle control, and apoptosis. PMID: 27851963
    2. Results show that YTHDC1 promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor SRSF3 while blocking SRSF10 mRNA binding. PMID: 26876937
    3. SRSF10 is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells PMID: 25091051
    4. In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells. PMID: 21984158
    5. Splicing thermotolerance is acquired through maintenance of SRSF10 phosphorylation and that this is mediated at least in part by Hsp27. PMID: 21135127
    6. Data show that SFRS13A expression was significantly associated with LDLR splicing efficiency in vivo. PMID: 20232416
    7. found to be dephosphorylated specifically in mitotic cells; show that dephosphorylated SRp38 is required for the observed splicing repression PMID: 12419250
    8. SRp38 plays a crucial role in cell survival under stress conditions by inhibiting the splicing machinery PMID: 14765198
    9. SRp38 contains two arginine- and serine-rich domains (RS), one of which has a unique, second-step repression activity, while both function together as a splicing repression domain. PMID: 16135820

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus speckle. Cytoplasm.
  • 蛋白家族：
    Splicing factor SR family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 16713

    OMIM: 605221

    KEGG: hsa:10772

    STRING: 9606.ENSP00000420195

    UniGene: Hs.3530



主站蜘蛛池模板： 亚洲老妇色熟女老太| 久久国产av影片| 亚洲丰满熟女一区二区v| 国产情侣一区二区三区| 久久精品免视看国产成人 | 中国xxx农村性视频| 色老头在线一区二区三区| 丰满少妇被猛烈进入高清播放| 久久久久99精品成人片牛牛影视| 中字幕久久久人妻熟女天美传媒 | 国产激情无码一区二区app| 伊人久久精品无码麻豆一区| 一本无码久本草在线中文字幕dvd| 国模欢欢炮交啪啪150| 亚洲综合熟女久久久40p| 亚洲人成黄网站69影院| 久久香蕉国产线看观看精品yw| 亚洲中文字幕无码日韩| 精品久久国产综合婷婷五月| 欧美成年网站色a| 麻豆高清免费国产一区| 亚洲a片国产av一区无码| 麻豆人妻无码性色av专区| 巨大欧美黑人xxxxbbbb| 精品欧美乱码久久久久久1区2区 | 日韩av片无码一区二区不卡电影 | 高潮爽死抽搐白浆gif视频| 精品无码成人片一区二区98| 欧美成人看片黄a免费看| 国产桃色无码视频在线观看| 玩50岁四川熟女大白屁股直播| 色妞色综合久久夜夜| 欧美又粗又长又爽做受| 欧美特级婬片毛多的少妇| 99久久精品免费看国产| 精品无码一区二区三区爱欲九九| 免费人成在线观看视频无码| 国产在线精品99一区不卡| 性做久久久久久久| 人人爽人人澡人人高潮| 在线资源天堂www|