在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SRPX2 Antibody

SRPX2 Antibody

  • 中文名稱：
    SRPX2兔多克隆抗體
  • 貨號：
    CSB-PA022690GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SRPX2
  • 別名：
    BPP antibody; CBPS antibody; PMGX antibody; RESDX antibody; SRPUL antibody; SRPX 2 antibody; SRPX2 antibody; SRPX2_HUMAN antibody; Sushi repeat containing protein SRPX2 antibody; Sushi repeat containing protein X linked 2 antibody; Sushi repeat protein antibody; Sushi repeat-containing protein SRPX2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SRPX2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
  • 基因功能參考文獻：
    1. SRPX2 potentially acts as an independent prognostic predictor and a drug-target for hepatocellular carcinoma patients. PMID: 28654796
    2. Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer. PMID: 25737434
    3. In rolandic epilepsy patients no major role was found for an association with SRPX2 or ELP4 genes. PMID: 24995671
    4. High SRPX2 expression is associated with gastric cancer. PMID: 24700475
    5. SRPX2 is an epilepsy- and language-associated gene that is a target of the foxhead box protein P2 (FoxP2) transcription factor. PMID: 24179158
    6. The SRPX2 protein contains the P-DUDES structural domain in its C-terminal region. This domain has significant albeit remote sequence similarity to thioredoxin-like domains, and is predicted to possess an oxidoreductase function. PMID: 209648
    7. Hypomethylation of SRPX2 appeared at the transition from adenoma to carcinoma, and was correlated with adenocarcinoma histology, microsatellite stability, and poor differentiation. PMID: 23115050
    8. SRPX2 is a novel chondroitin sulfate proteoglycan that is overexpressed in gastrointestinal cancer cells. PMID: 22242148
    9. The FOXP2-SRPX2/uPAR network provides exciting insights into molecular pathways underlying speech-related disorders. PMID: 20858596
    10. acts as regulator of ICAM1 and E-selectin during endotoxemia PMID: 20236627
    11. These findings suggest that Srpx2 regulates endothelial cell migration and tube formation and provides a new target for modulating angiogenesis. PMID: 19667118
    12. The involvement of SRPX2 in these disorders suggests an important role for SRPX2 in the perisylvian region critical for language and cognitive development. PMID: 16497722
    13. The R75K human-specific variation occurred in an important functional loop of the first sushi domain of SRPX2, indicating that this evolutionary mutation may have functional importance PMID: 17942002
    14. Interaction of SRPX2 with uPAR involved in the functioning, the development and disorders of the speech cortex. PMID: 18718938
    15. the biological functions of SRPX2 include cellular migration and adhesion to cancer cells. PMID: 19065654

    顯示更多

    收起更多

  • 相關疾病：
    Rolandic epilepsy with speech dyspraxia and mental retardation X-linked (RESDX)
  • 亞細胞定位：
    Secreted. Cytoplasm. Cell surface. Cell junction, synapse.
  • 組織特異性：
    Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed
  • 數據庫鏈接：

    HGNC: 30668

    OMIM: 300642

    KEGG: hsa:27286

    STRING: 9606.ENSP00000362095

    UniGene: Hs.306339



主站蜘蛛池模板： 人妻互换免费中文字幕| 衣服被扒开强摸双乳18禁网站| 国产成+人+综合+亚洲欧美丁香花| 亚洲欧美在线人成最新| 国产在线欧美日韩精品一区| 色综合久久婷婷五月| 精品97国产免费人成视频| 精品久久久久久成人av| 激情偷乱人成视频在线观看| 国产在线一区二区在线视频| 国产曰批免费视频播放免费| 欧洲熟妇色xxxx欧美老妇多毛| 日本成aⅴ人片日本伦| 亚洲久久中文字幕www网站| 久久99精品国产自在现线小黄鸭 | 尤物色综合欧美五月俺也去| 亚洲精品无码专区在线播放| 国产精品久久无码一区| 亚洲欧美丝袜精品久久| 亚洲 综合 欧美在线视频| 国产超碰人人做人人爱| 人人妻人人澡人人爽精品欧美| 亚洲 欧美精品suv| 精品视频一区二区三区在线观看 | 欧美xxxxx高潮喷水麻豆| 亚洲精品无码人妻无码| 狠狠色丁香久久综合| 亚洲精品一区二区三区四区五区| 色偷偷噜噜噜亚洲男人 | 97人妻无码一区| 国产一区视频一区欧美| 日韩精品人成在线播放 | 国产果冻豆传媒麻婆精东| 亚洲国产精品美女久久久久| 欧美人与动牲交zooz乌克兰| 好男人www社区视频在线资源| 337p日本欧洲亚洲大胆精筑| 亚洲欧美日韩精品久久| 亚洲无线观看国产精品| 久久国产精品人妻丝袜| 久久无码字幕中文久久无码|