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  4. SRP14 Antibody

SRP14 Antibody

  • 中文名稱：
    SRP14兔多克隆抗體
  • 貨號：
    CSB-PA022673LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA022673LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SRP14 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SRP14
  • 別名：
    18 kDa Alu RNA binding protein antibody; 18 kDa Alu RNA-binding protein antibody; Alu RNA-binding protein, 14-KD subunit antibody; ALURBP antibody; MGC14326 antibody; Signal recognition particle 14 kDa protein antibody; signal recognition particle 14kDa (homologous Alu RNA binding protein) antibody; SRP 14 antibody; SRP14 antibody; SRP14_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Signal recognition particle 14 kDa protein (2-107AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SRP14 Antibody (CSB-PA022673LA01HU)，的標記方式是Non-conjugated。對于SRP14 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA022673LB01HU SRP14 Antibody, HRP conjugated ELISA
    FITC CSB-PA022673LC01HU SRP14 Antibody, FITC conjugated
    Biotin CSB-PA022673LD01HU SRP14 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
  • 基因功能參考文獻：
    1. SRP14 mutant proteins with absence of a peptide elongation delay caused inefficient targeting of preproteins leading to defects in secretion, depletion of proteins in the endogenous membranes, and reduced cell growth. PMID: 18455985
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    SRP14 family
  • 數據庫鏈接：

    HGNC: 11299

    OMIM: 600708

    KEGG: hsa:6727

    STRING: 9606.ENSP00000267884

    UniGene: Hs.533732



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