在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SRGAP3 Antibody

SRGAP3 Antibody

  • 中文名稱：
    SRGAP3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA022663LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA022663LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SRGAP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SRGAP3
  • 別名：
    ARHGAP 14 antibody; ARHGAP14 antibody; Gbi antibody; ME GAP antibody; MEGAP antibody; Mental disorder associated GAP antibody; Mental disorder-associated GAP antibody; Rho GTPase activating protein 14 antibody; Rho GTPase-activating protein 14 antibody; SLIT ROBO Rho GTPase activating protein 3 antibody; SLIT-ROBO Rho GTPase-activating protein 3 antibody; srGAP 2 antibody; srGAP 3 antibody; srGAP2 antibody; srGAP3 antibody; SRGP 2 antibody; SRGP2 antibody; SRGP3_HUMAN antibody; WAVE associated Rac GTPase activating protein antibody; WAVE-associated Rac GTPase-activating protein antibody; WRP antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human SLIT-ROBO Rho GTPase-activating protein 3 protein (709-955AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SRGAP3 Antibody (CSB-PA022663LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SRGAP3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA022663LB01HU SRGAP3 Antibody, HRP conjugated ELISA
    FITC CSB-PA022663LC01HU SRGAP3 Antibody, FITC conjugated
    Biotin CSB-PA022663LD01HU SRGAP3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
  • 基因功能參考文獻(xiàn)：
    1. A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. PMID: 25819436
    2. Nuclear-localized srGAP3 interacts with Brg1. This interaction is mediated by the C-terminal of srGAP3 and the ATPase motif of Brg1. PMID: 24561795
    3. deletion of SRGAP3 provides the most convincing explanation for our patient's phenotype, and our observations lend further weight to a causative role of SRGAP3 haploinsufficiency in mental retardation. PMID: 24300292
    4. conclude that srGAP3 has tumor suppressor-like activity in HMECs, likely through its activity as a negative regulator of Rac1 PMID: 23108406
    5. putative role in severe mental retardation PMID: 12195014
    6. Data suggest that MEGAP negatively regulates cell migration by perturbing the actin and microtubule cytoskeleton and by hindering the formation of focal complexes. PMID: 16730001
    7. We found no association between SRGAP3/MEGAP haploinsufficiency and mental retardation. PMID: 19433673
    8. Current evidence suggests that SRGAP3 is the major determinant of mental retardation in distal 3p deletions. PMID: 19760623
    9. FNBP2, ARHGAP13, ARHGAP14 and ARHGAP4 constitute the FNBP2 family characterized by FCH, RhoGAP and SH3 domains. PMID: 12736724

    顯示更多

    收起更多

  • 相關(guān)疾病：
    A chromosomal aberration involving SRGAP3 is found in a patient with severe idiopathic mental retardation (PubMed:12195014). Translocation t(X;3)(p11.2;p25) (PubMed:12195014).
  • 組織特異性：
    Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19744

    OMIM: 606525

    KEGG: hsa:9901

    STRING: 9606.ENSP00000373347

    UniGene: Hs.654743



主站蜘蛛池模板： 亚洲综合无码久久精品综合| 97精品国自产在线偷拍| 国产伦人人人人人人性| 50岁熟妇的呻吟声对白| 92国产精品午夜福利免费| 人妻精油按摩bd高清中文字幕| 中文字幕v亚洲ⅴv天堂| 欧美亚洲国产手机在线有码| 国产成人啪精品视频网站午夜| 欧美大胆少妇bbw| 日本免费人成视频播放| 国产成人高清精品免费| 丰满少妇被猛烈进av毛片| 人人妻人人澡人人爽欧美二区| 午夜欧美精品久久久久久久| av无码人妻一区二区三区牛牛| 在教室伦流澡到高潮h麻豆| 少妇精品无码一区二区免费视频| 无码国产精品一区二区高潮| 青青草国产精品日韩欧美| 成人精品免费视频在线观看| 激情综合婷婷丁香五月蜜桃| 中文字幕无码免费久久| 亚洲色18禁成人网站www| 无翼乌工口全彩肉肉无遮挡18| 成人免费乱码大片a毛片| 国产成a人亚洲精v品无码性色| 国产精品无码永久免费不卡| 欧美午夜片欧美片在线观看| 亚洲日韩色欲色欲com| 曰韩人妻无码一区二区三区综合部| 亚洲国产婷婷香蕉久久久久久| 日本午夜免a费看大片中文4| 国产又黄又大又粗视频| 人人澡超碰碰97碰碰碰| 国产精品人妻系列21p| 欧美两根一起进3p在线观看| 激情内射亚洲一区二区三区爱妻| 一区二区无码免费视频网站| 日韩午夜理论片 中文字幕| 国产精品 视频一区 二区三区 |