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SPRY3 Antibody

  • 中文名稱:
    SPRY3兔多克隆抗體
  • 貨號:
    CSB-PA022623GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SPRY3
  • 別名:
    SPRY3 antibody; Protein sprouty homolog 3 antibody; Spry-3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SPRY3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
  • 基因功能參考文獻:
    1. SPRY3 is a candidate susceptibility locus for autism and related or over-lapping disorders such as ataxia. PMID: 26089202
    2. Spry 1, 2 and 3 expression was observed in placental tissue from all three trimesters PMID: 15950061
    3. the Sprouty/Caveolin-1 interaction modulates signaling in a growth factor- and Sprouty isoform-specific manner PMID: 16877379
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Sprouty family
  • 組織特異性:
    Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level). Expressed in the myocardium of the heart.
  • 數據庫鏈接:

    HGNC: 11271

    OMIM: 300531

    KEGG: hsa:10251

    STRING: 9606.ENSP00000302978

    UniGene: Hs.381912



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