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  4. SPRR1A Antibody, FITC conjugated

SPRR1A Antibody, FITC conjugated

  • 中文名稱(chēng)：
    SPRR1A兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA022610LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) SPRR1A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SPRR1A
  • 別名：
    SPRR1A antibody; Cornifin-A antibody; 19 kDa pancornulin antibody; SPRK antibody; Small proline-rich protein IA antibody; SPR-IA antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Cornifin-A protein (8-72AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
  • 基因功能參考文獻(xiàn)：
    1. mRNA levels of LELP1, SPRR1Av1, and SPRR1Av2 were significantly higher in the skin of patients with AD compared with the control group. PMID: 27304082
    2. the SPRR1A status might play an important role in the prognosis of postmenopausal breast carcinoma patients, especially that of progesterone receptor-positive subgroups. PMID: 25424702
    3. A expression may be useful as a prognostic factor for diffuse large B-cell lymphoma. PMID: 24886019
    4. Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. PMID: 18643845
    5. the deregulated increase in SPRR1A expression in chronic atopic skin lesions reflects an insufficient rise in SPRR transcripts, unable to compensate for the lack of LOR and thus contributing to the persistence of chronic atopic dermatitis skin lesions. PMID: 19672094

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  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Cornifin (SPRR) family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11259

    OMIM: 182265

    KEGG: hsa:6698

    STRING: 9606.ENSP00000307340

    UniGene: Hs.46320



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