在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPON2 Antibody

  • 中文名稱:
    SPON2兔多克隆抗體
  • 貨號:
    CSB-PA006509
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of COS-7 cells using Mindin Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SPON2
  • 別名:
    Differentially expressed in cancerous and non-cancerous lung cells 1 antibody; DIL 1 antibody; DIL-1 antibody; DIL1 antibody; DKFZp686G21139 antibody; FLJ16313 antibody; FLJ22401 antibody; FLJ34460 antibody; M spondin antibody; Mindin antibody; ORF Names: antibody; SPON 2 antibody; Spon2 antibody; SPON2_HUMAN antibody; Spondin 2 antibody; Spondin 2 extracellular matrix protein antibody; Spondin-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat,Monkey
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Mindin.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

引用文獻

產品評價

靶點詳情

  • 功能:
    Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).
  • 基因功能參考文獻:
    1. Egr-1 regulates mindin expression by directly binding to the mindin promoter; mindin suppresses colon cancer progression by blocking angiogenesis. PMID: 28991232
    2. Spondin-2 overexpression contributes to tumor aggressiveness and prognosis in gastric cancer. PMID: 28060752
    3. SPON2 is a transcriptional target of the metastasis gene MACC1. SPON2 induces cell motility in vitro and CRC metastasis in mice. In patients, SPON2 serves as prognostic indicator for CRC metastasis and survival, and might represent a promising target for therapeutic approaches. PMID: 26686083
    4. Data suggest that spondin-2 could be an independent diagnostic and prognostic biomarker of colon cancer. PMID: 25945835
    5. Mindin protects against vascular hyperplasia by suppression of abnormal VSMC proliferation, migration and phenotypic switching in an AKT-dependent manner. PMID: 25751394
    6. Using tissue microarray by immunohistostaining, we found SPON2 to be over-expressed in prostate cancer (PCa). SPON2 staining was more intense in Gleason score sum 7-8 and in PCa patients with metastasis. PMID: 22615945
    7. mindin serves as a novel mediator that protects against cardiac hypertrophy and the transition to heart failure by blocking AKT/GSK3beta and TGF-beta1-Smad signalling. PMID: 21632881
    8. High Mindin is associated with diabetic nephropathy in type 2 diabetes. PMID: 21098016
    9. Spondin 2, which is regulated by T(3), has an important role in cell invasion, cell migration, and hepatoma tumor progression. PMID: 19903741
    10. The structure of the F-spondin domain of mindin was determined at 1.8-A resolution. PMID: 19153605

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性:
    Expressed in normal lung tissue but not in lung carcinoma cell lines.
  • 數據庫鏈接:

    HGNC: 11253

    OMIM: 605918

    KEGG: hsa:10417

    STRING: 9606.ENSP00000290902

    UniGene: Hs.302963



主站蜘蛛池模板: 亚洲日韩av一区二区三区四区 | 国产精品ⅴ无码大片在线看 | 久天啪天天久久99久久| 亚洲国产老鸭窝一区二区三区| 天干夜天天夜天干天2004年| 国产熟女一区二区三区五月婷 | 亚洲日韩av一区二区三区中文| 四虎亚洲精品无码| 色哟哟最新在线观看入口| 国产95在线 | 亚洲| 国产精品岛国久久久久| 久久无码中文字幕无码| 国产精品玖玖玖在线| аⅴ资源天堂资源库在线| 国产免费无码一区二区视频| 9久9久女女热精品视频在线观看| 人妻三级日本香港三级极97| 艳妇臀荡乳欲伦交换h在线观看| 小辣椒福利视频导航| 影音先锋日日狠狠久久| 欧美变态口味重另类在线视频| 亚洲人亚洲精品成人网站| 午夜福利理论片高清在线| 成人做爰高潮片免费视频| 日日av拍夜夜添久久免费| 欧美成人精品第一区二区三区| 亚洲国产精品国自产拍电影 | 亚洲成a人无码| 人妻少妇精品视频一区二区三区| 久久精品国产精品久久久| 成人免费大片黄在线观看com| 9色国产深夜内射| 亚洲乱亚洲乱妇24p| 亚洲精品无码久久久久av老牛 | 亚洲 制服 丝袜 无码 在线| 精品免费国产一区二区三区四区| 香港台湾经典三级a视频| 中文字幕日韩人妻不卡一区| 国产又色又爽又刺激在线播放 | 国产午夜精品一区二区三区极品| 青青草国产免费久久久下载|