在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPOCK1 Antibody, Biotin conjugated

  • 中文名稱:
    SPOCK1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA730785LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SPOCK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SPOCK1
  • 別名:
    SPOCK1 antibody; SPOCK antibody; TIC1 antibody; TICN1 antibody; Testican-1 antibody; Protein SPOCK antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Testican-1 protein (290-435AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.
  • 基因功能參考文獻:
    1. Testican-1 blood level is related to the severity of sepsis and Testican-1 could be used as a biomarker to determine the severity of sepsis. PMID: 29315764
    2. Overexpression of SPOCK1was confirmed in head and neck squamous cell carcinoma clinical specimens. Overexpression of SPOCK1 contributes to the aggressive nature of HNSCC. PMID: 29233721
    3. High SPOCK1 expression is associated with castration-resistant prostate cancer. PMID: 28534948
    4. downregulation of both strands of pre-miR-150 and overexpression of SPOCK1 are involved in esophageal squamous cell carcinoma (ESCC). pathogenesis. The involvement of passenger strand miRNAs in the regulation of cancer cell aggressiveness is a novel concept in RNA research PMID: 28659612
    5. is significantly upregulated in osteosarcoma tissue. PMID: 28869894
    6. Functional assessment in cocultures demonstrated that SPOCK1 strongly affects the composition of the extracellular collagen matrix and by doing so, enables invasive tumor cell growth in Pancreatic ductal adenocarcinoma. PMID: 28486750
    7. Transcriptomic analysis of EPCR-silenced tumors unveiled an effect mediated by matricellular SPOCK1/testican 1. SPOCK1 silencing suppressed in vitro 3D growth. SPOCK1 ablation decreased orthotopic tumor growth and reduced metastatic osteolytic tumors. High SPOCK1 levels were also associated with poor clinical outcome in a subset of breast cancer patients. PMID: 28103946
    8. a novel TGF-beta-induced myoepithelial marker and enhanced invasion in breast cancer cells and correlated with poor prognosis PMID: 27626636
    9. Our results suggested that microRNA-129-5p could directly specifically suppress SPOCK1, which might be one of the potential mechanisms in inhibiting cell processes including viability, proliferation, cell mitosis, migration, and invasiveness of gastric cancer cells. PMID: 28653880
    10. SPOCK1 expression is significantly up-regulated in colorectal cancer tissues and associated with tumor size and stage. SPOCK1 stimulates the PI3K/AKT signaling pathway to inhibit cell apoptosis and promote tumor growth. PMID: 27889608
    11. findings suggest that SPOCK1 is a critical mediator of tumor growth and metastasis in prostate cancer PMID: 27486308
    12. Knockdown of SPOCK1 inhibits the proliferation. PMID: 28281964
    13. This study suggests that SPOCK1 promotes proliferation, migration and invasion in glioma cells by activating PI3K/AKT and Wnt/beta-catenin pathways, which provides a potential theoretical basis for clinical treatment of glioma. PMID: 27108836
    14. SPOCK1 is highly expressed in ovarian cancer.SPOCK1 contributes to ovarian cancer development and metastasis. PMID: 26638890
    15. These results suggest that up-regulation of SPOCK1 in ESCC induces EMT, thus promotes migration and invasion in ESCC cells. PMID: 26077618
    16. Collectively, altered expression of PKP1 and SPOCK1 appears to be a frequent and critical event in prostate cancer PMID: 26138584
    17. SPOCK1 activates PI3K/Akt signaling. PMID: 25623055
    18. Testican-1-induced EMT signaling. PMID: 23873022
    19. this study showed that SPOCK1 is a novel metastasis related biomarker in lung cancer and may be new diagnostic and therapeutic target for lung cancer. PMID: 24134845
    20. In the present study, we showed that SPOCK1 could inhibit apoptosis and promote cancer invasion. PMID: 23022495
    21. Significant overexpression of osteonectin mRNA is associated with pancreatic cancer PMID: 16596217
    22. SPOCK gene underlies variation of age at menarche PMID: 19282985

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 數據庫鏈接:

    HGNC: 11251

    OMIM: 602264

    KEGG: hsa:6695

    STRING: 9606.ENSP00000282223

    UniGene: Hs.596136



主站蜘蛛池模板: 国产无套内射普通话对白| 午夜亚洲国产理论片二级港台二级 | 中文字幕人妻丝袜二区| 亚洲aⅴ天堂av天堂无码麻豆| 又色又污又爽又黄的网站 | 综合激情五月综合激情五月激情1 h漫全彩纯肉无码网站 | 久久国产36精品色熟妇| 无码吃奶揉捏奶头高潮视频| 六月丁香亚洲综合在线视频| 国产伦精品一区二区三区免.费| 波多野结av衣东京热无码专区| 青青草国产精品日韩欧美| 综合欧美亚洲日本一区| 香蕉视频在线精品视频| 人妻激情另类乱人伦人妻| 精品国产美女av久久久久| 成人黄网站高清免费视频 | 妖精色av无码国产在线看| 国产亚洲人成无码网在线观看| 67194熟妇在线观看线路1| 无遮挡国产高潮视频免费观看 | 久久久久中文伊人久久久| 军人粗大的内捧猛烈进出视频| 亚洲欧洲日产国码无码久久99| 99re6热精品视频在线观看| 久久高清超碰av热热久久| 国内精品久久久久久久97牛牛| 国产综合精品| 亚洲欧美人成网站aaa| 国产在线高清理伦片a| 99国产欧美久久久精品| 两个奶头被吃高潮视频| 成人麻豆日韩在无码视频| 亚洲一区爱区精品无码| 性色av无码久久一区二区三区| 国产一区二区三区四区五区加勒比| 精品偷拍被偷拍在线观看| 国产成人久久综合第一区| 性生交大片免费看| 亚洲精品国产精品无码国模| 在线播放偷拍一区精品|