在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPNS2 Antibody, HRP conjugated

  • 中文名稱:
    SPNS2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA815559LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SPNS2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SPNS2
  • 別名:
    SPNS2 antibody; Protein spinster homolog 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein spinster homolog 2 protein (1-140AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts a a crucial lysosphingolipid sphingosine 1-phosphate (S1P) transporter involved in S1P secretion and function. S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking.
  • 基因功能參考文獻:
    1. our data demonstrate that Spns2 and S1P have a crucial effect on proximal tubular epithelial cells by regulating an inflammatory process and a subsequent fibrotic reaction, and also by influencing other tubular transporters that are involved in the pathophysiology of inflammatory and fibrotic kidney diseases. PMID: 29772789
    2. Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development PMID: 27562371
    3. In both macrophage and epithelial cell types, Spns2 was also found localized to cytoplasm and the nucleus, in line with a predicted bipartile Nuclear Localization Signal at the position aa282 of the human Spns2 sequence PMID: 29112690
    4. A novel role for Spns2 and S1P1&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury. PMID: 27343196
    5. Spns2 plays key roles in regulating the cellular functions in non-small cell lung cancer (NSCLC) cells PMID: 25330231
    6. mammals. These findings indicate that Spns2 is required for normal maintenance of the endocochlear potential and hence for normal auditory function, and support a role for S1P signalling in hearing. PMID: 25356849
    7. Spns2 is an S1P transporter in vivo that plays a role in regulation not only of blood S1P but also lymph node and lymph S1P levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization. PMID: 23180825
    8. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720. PMID: 21084291

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily, Spinster (TC 2.A.1.49) family
  • 數據庫鏈接:

    HGNC: 26992

    OMIM: 612584

    KEGG: hsa:124976

    STRING: 9606.ENSP00000333292

    UniGene: Hs.22824



主站蜘蛛池模板: 国产免费人成在线视频网站| 给我免费的视频在线观看 | 国产亚洲精品a在线| 女学生14毛片视频片二毛| 在线|国产精品女主播阳台| 国产精品久久久久久影视不卡| 越南毛茸茸的少妇| 欧美丰满熟妇hdxx| 久久综合五月丁香久久激情| 2019久久久最新精品| 无码人妻精品一区二区蜜桃色欲| 性生交大片免费看女人按摩摩| 国产av福利第一精品| 久久99亚洲精品久久频| 久久久久久久综合色一本| 国产精品亚洲成在人线| 国产日产欧产美韩系列麻豆 | 国产精品无码无需播放器| 午夜福利一区二区三区高清视频| 亚洲一本一道一区二区三区| 538在线精品视频| 午夜精品久久久内射近拍高清| 午夜亚洲国产理论片中文飘花| 亚洲一区在线观看尤物| 国产麻豆md传媒视频| 中文字幕无码日韩专区| 情侣激情18内射骚话国产| 成人aaa片一区国产精品| 国内大量揄拍人妻精品視頻| 亚洲国产精品久久久久4婷婷| 韩国三级中文字幕hd| 久久天天躁狠狠躁夜夜av| 免费看国产精品3a黄的视频| 精品卡1卡2卡三卡免费网站| 夫妇交换性三中文字幕| 久久97国产超碰青草| 成人无码午夜在线观看| 18禁黄网站禁片免费观看| 亚洲精品国产嫩草在线观看东京热| 亚洲中文字幕国产综合| 同性男男黄g片免费网站|