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SPCS1 Antibody, HRP conjugated

  • 中文名稱：
    SPCS1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA896543LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SPCS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SPCS1
  • 別名：
    HSPC033 antibody; Microsomal signal peptidase 12 kDa subunit antibody; OTTHUMP00000206959 antibody; signal peptidase 12kDa antibody; Signal peptidase complex subunit 1 antibody; signal peptidase complex subunit 1 homolog (S. cerevisiae) antibody; SPase 12 kDa subunit antibody; SPC1 antibody; SPC12 antibody; SPCS1 antibody; SPCS1_HUMAN antibody; YJR010C-A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Signal peptidase complex subunit 1 protein (70-102AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.; (Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV). Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1. In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2.
  • 基因功能參考文獻：
    1. the results demonstrate that SPCS1 affects viral replication by interacting with NS2B, thereby influencing the posttranslational processing of Japanese Encephalitis Virus proteins and the assembly of virions. PMID: 29593046
    2. SPCS1 plays a key role in the formation of the membrane-associated NS2-E2 complex via its interaction with NS2 and E2, which leads to a coordinating interaction between the structural and non-structural proteins PMID: 24009510
  • 亞細胞定位：
    Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SPCS1 family
  • 數據庫鏈接：

    HGNC: 23401

    OMIM: 610358

    KEGG: hsa:28972

    STRING: 9606.ENSP00000233025

    UniGene: Hs.11125



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