在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPARCL1 Antibody

  • 中文名稱:
    SPARCL1兔多克隆抗體
  • 貨號:
    CSB-PA022487GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SPARCL1
  • 別名:
    Ecm2 antibody; Extracellular matrix protein 2 antibody; Hevin antibody; High endothelial venule protein antibody; MAST 9 antibody; mast9 antibody; Matrix glycoprotein Sc1 antibody; PIG33 antibody; proliferation inducing protein 33 antibody; RAGS1 antigen antibody; SC1 antibody; SPARC like 1 antibody; SPARC-like protein 1 antibody; Sparcl1 antibody; SPRL1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SPARCL1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. SC1 levels were independently associated with ischemic stroke severity evaluated by the NIHSS. PMID: 29102542
    2. The results of this study suggest that the SPARCL1 accelerates Alzheimer's Disease pathogenesis and thus link neuroinflammation with widespread changes in brain structure and function during aging. PMID: 29154276
    3. The present study demonstrated that the expression of SPARCL1 was downregulated in renal cell carcinoma (RCC) cells and tissues, however, the overexpression of SPARCL1 inhibited RCC cell migration and invasion. PMID: 28944877
    4. This study demonstrated the SPARCL1-containing neurons in the human brainstem and sensory ganglion. PMID: 27357901
    5. tumor endothelial cells heterogeneity is regulated by SPARCL1, which promotes the cell quiescence and vessel homeostasis contributing to the favorable prognoses associated with Th1-tumor microenvironments colorectal carcinomas. PMID: 27721236
    6. SPARCL1 is involved in the tumorigenesis of hilar cholangiocarcinoma and may serve as a novel molecular biomarker for patients' outcome. PMID: 26490986
    7. Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression PMID: 26294211
    8. SPARCL1 expression did not inhibit tumor cell proliferation in vitro. By contrast, SPARCL1 did suppress tumor cell migration and invasiveness in vitro and tumor metastatic growth in vivo, conferring improved survival in xenograft mouse models PMID: 23916135
    9. radiotherapy causes an increase in SPARCL1 expression; SPARCL1 may have a role in survival in rectal cancer patients PMID: 24661672
    10. SPARCL1 functions as a tumor suppressor promoting differentiation possibly via MET, which inhibits the aggressiveness of colorectal cancers PMID: 22891198
    11. Sparc-like protein 1 expression correlates with glioma grade, suggesting the possible role for this protein in the progression of this malignancy. PMID: 22909274
    12. SPARCL1 is a potent regulator of cell migration/invasion and its loss is independently associated with prostate cancer recurrence. PMID: 22927397
    13. Data suggest that the expression of SPARCL1 protein might be a valuable biomarker for early diagnosis in colorectal cancers and further predicting patients' prognosis. PMID: 21887554
    14. Down-regulated SPARCL1 is associated with gastric cancer. PMID: 22161898
    15. Data suggest that SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are potential prognostic markers in colorectal cancer. PMID: 21528083
    16. Overall, these results suggested that the C-t of hevin contains important determinants for interaction with myocilin. PMID: 16316624
    17. hevin can modulate the structure of dermal extracellular matrix, specifically by its regulation of decorin levels and collagen fibril assembly PMID: 16844696
    18. Despite proteomic studies in CSF from MS patients suggested an important role for SPARCL1 in the development of the disease, SPARCL1 gene does not appear to act as susceptibility factor for MS in the population investigated here. PMID: 17825989
    19. A transgenic mouse model in which SPARCL1 is expressed in radial glia provides a novel in vivo system for evaluating the role of SPARCL1 in brain development and function. PMID: 18381651

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    SPARC family
  • 組織特異性:
    Highly expressed in lymph node, brain, heart, lung, skeletal muscle, ovary, small intestine, and colon, with lower levels in placenta, pancreas, testis, spleen, and thymus, and no expression in kidney, liver, and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 11220

    OMIM: 606041

    KEGG: hsa:8404

    STRING: 9606.ENSP00000282470

    UniGene: Hs.62886



主站蜘蛛池模板: 久久国产成人精品国产成人亚洲| 国产精品高清网站| 啦啦啦www播放日本观看| 久久人妻少妇嫩草av蜜桃| 影音先锋男人站| 在线视频 亚太 国产 欧美 一区二区| 日韩a人毛片精品无人区乱码| 久久久久久无码av成人影院| 日本免费大黄在线观看| 国产一区二区在线视频| 天堂а√在线最新版中文| 中文天堂最新版资源www官网| 国产奶头好大揉着好爽视频| 女人18片毛片60分钟| 一边捏奶头一边啪高潮视频 | 国产午夜亚洲精品一区| 精品国产在天天在线观看| 少妇被躁爽到高潮无码久久| 国产真实露脸乱子伦原著| 亚洲国产精品第一区二区三区| 久久经精品久久精品免费观看| 深夜福利在线观看视频| 色天天天综合色天天| 精品系列无码一区二区三区 | 国产精品久久久久久无码| 手机看片国产av无码| 亚洲精品自产拍在线观看亚瑟| 亚洲中文字幕无码一区| 精品亚洲一区二区三区在线观看 | 天堂va欧美va亚洲va好看va| 一卡二卡3卡四卡网站精品| 亚洲日韩国产av无码无码精品| 亚洲精品第一国产综合亚av| 国产精品麻豆成人av网| 狠狠噜天天噜日日噜视频麻豆| 国产激情久久久久久熟女老人av| 成人看片黄a免费看在线| 青青草国产精品人人爱| 亚洲一区二区三区四区| 亚洲精品一区二区三区不卡| 免费一区二区三区成人免费视频|