在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPAG6 Antibody, FITC conjugated

  • 中文名稱:
    SPAG6兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA022467LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SPAG6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SPAG6
  • 別名:
    axoneme central apparatus protein antibody; DKFZp434I153 antibody; MGC26276 antibody; PF16 antibody; PF16 protein homolog antibody; Protein PF16 homolog antibody; Repro SA 1 antibody; Repro-SA-1 antibody; SPAG6 antibody; SPAG6_HUMAN antibody; Sperm associated antigen 6 antibody; Sperm flagellar protein antibody; Sperm-associated antigen 6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Sperm-associated antigen 6 protein (343-428AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.
  • 基因功能參考文獻:
    1. These results demonstrate that SPAG6 silencing induces PTEN expression to regulate apoptosis though the PI3K/AKT pathway, indicating that SPAG6 may be a potential therapeutic target for myelodysplastic syndromes. PMID: 29749435
    2. SPAG6 and L1TD1 are tumor-specifically methylated in NSCLCs and that DNA methylation is involved in the transcriptional regulation of these genes. Moreover, in vitro as well as in vivo experiments revealed tumor-cell growth suppressing properties of L1TD1 in NSCLC cells. PMID: 28093071
    3. Study demonstrates that SPAG6 may regulate apoptosis through the TRAIL signal pathway by inhibiting the expression of FADD and the interactions between FADD and the TRAIL death receptors. PMID: 28393201
    4. studies demonstrate a role for Spag6 in the pathogenesis of OM in mice, possibly through its role in the regulation of cilia/basal body polarity through the PCP-dependent mechanisms in the middle ear and Eustachian tubes. PMID: 25393619
    5. These findings demonstrate that SPAG6 might have a role in malignant myeloid hematologic cell proliferation and apoptosis by regulating caspase proteins and p53, suggesting that SPAG6 may be a potential therapeutic target. PMID: 25405588
    6. SPAG6 is a S-SOX5 target gene, indicating a key role for S-SOX5 in the formation and function of motile cilia. PMID: 20668334
    7. Data describe the cloning of human and mouse Pf20 proteins that interact with Spag6 protein. PMID: 12391165

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme.
  • 組織特異性:
    Highly expressed in testis.
  • 數據庫鏈接:

    HGNC: 11215

    OMIM: 605730

    KEGG: hsa:9576

    STRING: 9606.ENSP00000365811

    UniGene: Hs.655170



主站蜘蛛池模板: 国产亚洲精品综合一区| 成人无码免费视频在线播| 国产主播一区二区三区在线观看| 高潮潮喷奶水飞溅视频无码| 亚洲丰满熟女一区二区v| 久久国产成人精品国产成人亚洲| 久久久这里只有精品10| 欧美日本特级婬片视频| 国产精品成人免费视频网站京东| 激情内射亚州一区二区三区爱妻| 国产性生交xxxxx免费| 香蕉欧美成人精品a∨在线观看| 亚洲精品一区二区中文字幕| 国产人妻大战黑人20p| av天堂永久资源网| 国产三级在线观看免费| 亚洲成成品网站源码中国有限公司 | 久久精品99无色码中文字幕| 午夜嘿嘿嘿影院| 麻豆av福利av久久av| 狠狠综合亚洲综合亚洲色| 韩国三级无码hd中文字幕| 人妻少妇av中文字幕乱码| 天堂а√在线中文在线| 美乳丰满人妻无码视频| 国产av无码精品色午夜| 亚洲成a人v欧美综合天堂麻豆| 国产午夜福利在线播放| 亚洲国产成人精品福利| 亚洲精品一卡2卡三卡4卡 | 免费观看日本污污ww网站| 亚洲成a人片在线观看www| 亚洲vs日韩vs欧美vs久久| 亚洲欧美国产国产一区二区三区| 性一交一乱一乱一视频 | 精产国品一二三产品麻豆| 国产极品粉嫩福利姬萌白酱| 国产精品成人久久久久久久| 国产午夜亚洲精品一区| 久久亚洲国产成人精品性色| 精品久久久久久无码专区不卡|