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  4. SPACA3 Antibody

SPACA3 Antibody

  • 中文名稱：
    SPACA3兔多克隆抗體
  • 貨號：
    CSB-PA022454GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SPACA3
  • 別名：
    SPACA3 antibody; LYC3 antibody; LYZL3 antibody; SLLP1 antibody; SPRASA antibody; UNQ424/PRO862Sperm acrosome membrane-associated protein 3 antibody; Cancer/testis antigen 54 antibody; CT54 antibody; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17 antibody; Lysozyme-like protein 3 antibody; Sperm lysozyme-like protein 1 antibody; Sperm protein reactive with antisperm antibodies antibody; Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3 antibody; membrane form; Sperm acrosome membrane-associated protein 3 antibody; processed form] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SPACA3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
  • 基因功能參考文獻：
    1. The levels of antibodies reactive with SPRASA were elevated in infertile women. PMID: 25038051
    2. SLLP1 represents a promising target for the immunotherapy of multiple myeloma. PMID: 26088750
    3. Authors present evidence that the variants could affect the expression levels or function of SPRASA, thereby affecting a couple's fertility. PMID: 24872021
    4. SLLP1 could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane PMID: 12606493
    5. SLLP1 is capable of eliciting B-cell immune responses in vivo in cancer-bearing individuals. PMID: 15475442

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  • 亞細胞定位：
    [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein.; [Isoform 2]: Secreted.
  • 蛋白家族：
    Glycosyl hydrolase 22 family
  • 組織特異性：
    The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
  • 數據庫鏈接：

    HGNC: 16260

    OMIM: 612749

    KEGG: hsa:124912

    STRING: 9606.ENSP00000269053

    UniGene: Hs.434112



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