在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPA17 Antibody

  • 中文名稱:
    SPA17兔多克隆抗體
  • 貨號:
    CSB-PA022451GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Band 34 antibody; Cancer/testis antigen 22 antibody; CT22 antibody; SP17 1 antibody; Sp17-1 antibody; SP17_HUMAN antibody; SPA17 antibody; Sperm autoantigenic protein 17 antibody; Sperm protein 17 antibody; Sperm surface protein Sp17 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SPA17
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.
  • 基因功能參考文獻:
    1. Sp17 and ASP cancer/testis antigens were found in ciliated cells of four ciliated hepatic foregut cysts (CHFCs). Further characterization of Sp17 and ASP in patients with CHFCs may provide significant clues for understanding the molecular mechanisms underlying their predisposition to develop squamous cell carcinomas. PMID: 25600306
    2. dendritic cells from human umbilical cord blood modulated for SP17 expression induced antigen-specific anti-tumor immunity against SP17(+) non-small cell lung cancer. PMID: 26300426
    3. SP17/AKAP4/PTTG1 are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients. PMID: 25739119
    4. NY-ESO-1 and SP17 was not significantly associated with a specific histotype, but high-level GAGE expression was more frequent in squamous cell carcinoma. GAGE expression was demonstrated to be significantly higher in stage II-IIIa than stage I NSCLC. PMID: 24103781
    5. Sp17 is highly expressed in hepatocellular carcinoma cells PMID: 23923079
    6. SP17 was expressed in many cancer types with an overall frequency of 12%. SP17 was most frequently expressed in a different set of cancer types than MAGE-A and GAGE antigens and rarely overlapped with these proteins. PMID: 23137323
    7. Sperm protein 17 is highly expressed in endometrial and cervical cancers. PMID: 20712874
    8. Data show that cisplatin induced decrease in Sp17 levels was due to transcriptional inhibition and cisplatin-resistant cell lines did not show this decrease in Sp17 levels in response to cisplatin treatment. PMID: 19685492
    9. Sp17 has different expression patterns in cancer cell lines as compared to normal non-testes tissues and a potential pathogenic role in diseased cells PMID: 12213290
    10. focuses on the characterization of the genomic organization of an intron-containing gene and establishes a new transcription model PMID: 12393185
    11. expression of Sp17, a thought to be gamete-specific protein, in the synoviocytes of 8/8 female rheumatoid arthritis patients PMID: 12739786
    12. identification of a nonapeptide sequence within the Sp17 protein that is predicted to have a high binding affinity for HLA-A1 molecules PMID: 14566839
    13. Sp17 is expressed in the cell nucleus of ovarian neoplasms PMID: 14712480
    14. Sp17 gene expression in myeloma cells is regulated by promoter methylation PMID: 15381930
    15. Overexpression of sperm protein 17 is associated with esophageal cancer PMID: 17230514
    16. in vitro cultured, monoclonal, cytotoxic T lymphocytes (derived either from advanced OC patients or from healthy donors), specific for sperm protein 17, can eradicate human metastatic OC cells. PMID: 18779750
    17. Results suggest a possible role of Sp17 in regulating sperm maturation, capacitation, acrosomal reaction and interactions with the oocyte zona pellucida during the fertilization process. PMID: 19604394
    18. HSp17 plays a role in metastatic disease and resistance of epithelial ovarian carcinoma to chemotherapy PMID: 19744347

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Peripheral membrane protein.
  • 組織特異性:
    Testis and sperm specific.
  • 數據庫鏈接:

    HGNC: 11210

    OMIM: 608621

    KEGG: hsa:53340

    STRING: 9606.ENSP00000227135

    UniGene: Hs.286233



主站蜘蛛池模板: 秋霞最新高清无码鲁丝片| 人妻精油按摩bd高清中文字幕| 波多野42部无码喷潮在线| 欧美色欧美亚洲日韩在线播放 | 亚洲va久久久噜噜噜久久4399| 国产重口老太和小伙乱| 国产人成无码视频在线1000| 久久人人爽人人爽人人片av东京热| 久久久久有精品国产麻豆| 高潮毛片无遮挡高清免费视频| 国产牛仔裤网站精品| 中文字幕乱码亚洲无线三区| 欧洲美女与动zooz| 免费毛片手机在线播放| 日韩人妻ol丝袜av一二区| 亚洲精品夜夜夜| 亚洲不乱码卡一卡二卡4卡5| 久久精品国产只有精品2020| 久久久久亚洲精品| 久久精品国产大片免费观看| 亚洲国产精品综合久久网络| 亚洲aⅴ无码专区在线观看| 青青草国产免费国产是公开| 一区二区三区无码高清视频| 国内揄拍国内精品少妇国语| 亚洲欧美综合国产精品二区| 性色香蕉av久久久天天网| 看免费真人视频网站| 国产精品爆乳奶水无码视频免费| 午夜国产成人片在线播放| 成人婷婷网色偷偷亚洲男人的天堂| 亚洲国产日韩欧美一区二区三区| av无码天堂一区二区三区| 色99久久久久高潮综合影院| www国产精品内射熟女| 成人国产网站v片免费观看| 天堂va视频一区二区| 精品国产第一国产综合精品| 99久久精品无码一区二区毛片| 18禁超污无遮挡无码网址| 国产精品无码v在线观看|