在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SNTA1 Antibody

SNTA1 Antibody

  • 中文名稱：
    SNTA1兔多克隆抗體
  • 貨號：
    CSB-PA289378
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA289378(SNTA1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 80 μg, Lane 1-2: Human colon cancer and normal stomach tissue, Primary antibody: CSB-PA289378(SNTA1 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SNTA1
  • 別名：
    59 kDa dystrophin-associated protein A1 acidic component 1 antibody; Acidic alpha 1 syntrophin antibody; Alpha 1 syntrophin antibody; Alpha-1-syntrophin antibody; dJ1187J4.5 antibody; Dystrophin associated protein A1 59kDa acidic component antibody; LQT12 antibody; OTTHUMP00000030650 antibody; Pro-TGF-alpha cytoplasmic domain-interacting protein 1 antibody; SNT1 antibody; Snta1 antibody; SNTA1_HUMAN antibody; Syntrophin 1 antibody; Syntrophin-1 antibody; TACIP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SNTA1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
  • 基因功能參考文獻：
    1. not associated with sudden infant death syndrome PMID: 28520217
    2. Low SNTA expression is associated with non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma. PMID: 28941732
    3. A novel SNTA1 variant is likely causative for drug induced long-QT syndrome by augmenting the late sodium current. PMID: 27028743
    4. In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes. PMID: 25757662
    5. our results present a possible mechanism of Rac1 activation involving SNTA1 and emphasise its role in ROS generation, cell migration, and acquisition of malignancy. PMID: 24434436
    6. Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. PMID: 24014171
    7. alpha-Syntrophin, which resides in nuclei of myocytes, functions as the upstream mediator of nuclear nNOS translocation and nNOS-dependent mitochondrial biogenesis. PMID: 24235139
    8. Calcium homeostasis mishandling in Duchenne muscular dystrophy myotubes depends on store operated calcium entry under the influence alpha1-syntrophin regulation as well as TRPV2-dependant cation influx. PMID: 23426965
    9. The combined mutations of A261V-SNTA1 plus R800L-SCN5A increase the INa current late/peak ratio and time constants of current decay. PMID: 23376825
    10. In contrast to stomach, lung, colon and rectal cancers, SNTA1 protein was found to be downregulated in esophageal cancers and upregulated in breast cancer. PMID: 21091386
    11. alpha1D-adrenergic receptors are regulated by syntrophins through a PDZ domain-mediated interaction PMID: 16533813
    12. These results establish an SNTA1-based nNOS complex attached to SCN5A as a key regulator of sodium current and suggest that SNTA1 be considered a rare long QT syndrome-susceptibility gene. PMID: 18591664
    13. SNTA1 is a new susceptibility gene for LQTS. A257G-SNTA1 can cause gain-of-function of Na(v)1.5 similar to the LQT3. PMID: 19684871
    14. Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. PMID: 20009079

    顯示更多

    收起更多

  • 相關疾病：
    Long QT syndrome 12 (LQT12)
  • 亞細胞定位：
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Syntrophin family
  • 組織特異性：
    High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
  • 數據庫鏈接：

    HGNC: 11167

    OMIM: 601017

    KEGG: hsa:6640

    STRING: 9606.ENSP00000217381

    UniGene: Hs.31121



主站蜘蛛池模板： 亚洲人成人网站在线观看| 动漫成人无码精品一区二区三区| 国产午夜鲁丝无码拍拍| 欧美综合自拍亚洲图久青草| 亚洲精品乱码久久久久蜜桃| 中国少妇内射xxxx狠干| 白又丰满大屁股bbbbb| 天天操夜夜操| 日韩免费码中文在线观看| 亚洲欧美第一成人网站7777| 久久中文字幕人妻熟av女| 欧美z0zo人禽交欧美人禽交| 久久www成人看片免费不卡| 日韩精品无码不卡无码| 国产jk精品白丝av在线观看| 亚洲乱亚洲乱妇| 四房播色综合久久婷婷| 久久久国产精品va麻豆| 亚洲第一福利网站在线观看 | 大地资源网第二页免费观看| 少妇无码av无码专区线| 伊人久久丁香色婷婷啪啪| 婷婷丁香五月亚洲中文字幕| 337p大胆啪啪私拍人体| 一本一道av无码中文字幕| 日韩a片无码一区二区三区电影| 国产精品久久久久久久久绿色| 特级毛片爽www免费版| 国产精品沙发系列| 一色屋精品视频在线观看免费| 露脸内射熟女--69xx| 欧美亚洲日韩国产人成在线播放 | 久久99国产精品久久99| 亚洲欧美国产精品久久久久久久| 国产桃色无码视频在线观看| 欧美老肥妇多毛xxxxx| 欧美大屁股熟妇bbbbbb| 99久久精品国产一区二区三区 | 亚洲最大成人综合网720p| 国内偷窥一区二区三区视频| 人妻熟女一区二区aⅴ千叶宁真|