在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SNTA1 Antibody

SNTA1 Antibody

  • 中文名稱：
    SNTA1兔多克隆抗體
  • 貨號：
    CSB-PA289378
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA289378(SNTA1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 80 μg, Lane 1-2: Human colon cancer and normal stomach tissue, Primary antibody: CSB-PA289378(SNTA1 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SNTA1
  • 別名：
    59 kDa dystrophin-associated protein A1 acidic component 1 antibody; Acidic alpha 1 syntrophin antibody; Alpha 1 syntrophin antibody; Alpha-1-syntrophin antibody; dJ1187J4.5 antibody; Dystrophin associated protein A1 59kDa acidic component antibody; LQT12 antibody; OTTHUMP00000030650 antibody; Pro-TGF-alpha cytoplasmic domain-interacting protein 1 antibody; SNT1 antibody; Snta1 antibody; SNTA1_HUMAN antibody; Syntrophin 1 antibody; Syntrophin-1 antibody; TACIP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SNTA1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
  • 基因功能參考文獻：
    1. not associated with sudden infant death syndrome PMID: 28520217
    2. Low SNTA expression is associated with non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma. PMID: 28941732
    3. A novel SNTA1 variant is likely causative for drug induced long-QT syndrome by augmenting the late sodium current. PMID: 27028743
    4. In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes. PMID: 25757662
    5. our results present a possible mechanism of Rac1 activation involving SNTA1 and emphasise its role in ROS generation, cell migration, and acquisition of malignancy. PMID: 24434436
    6. Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. PMID: 24014171
    7. alpha-Syntrophin, which resides in nuclei of myocytes, functions as the upstream mediator of nuclear nNOS translocation and nNOS-dependent mitochondrial biogenesis. PMID: 24235139
    8. Calcium homeostasis mishandling in Duchenne muscular dystrophy myotubes depends on store operated calcium entry under the influence alpha1-syntrophin regulation as well as TRPV2-dependant cation influx. PMID: 23426965
    9. The combined mutations of A261V-SNTA1 plus R800L-SCN5A increase the INa current late/peak ratio and time constants of current decay. PMID: 23376825
    10. In contrast to stomach, lung, colon and rectal cancers, SNTA1 protein was found to be downregulated in esophageal cancers and upregulated in breast cancer. PMID: 21091386
    11. alpha1D-adrenergic receptors are regulated by syntrophins through a PDZ domain-mediated interaction PMID: 16533813
    12. These results establish an SNTA1-based nNOS complex attached to SCN5A as a key regulator of sodium current and suggest that SNTA1 be considered a rare long QT syndrome-susceptibility gene. PMID: 18591664
    13. SNTA1 is a new susceptibility gene for LQTS. A257G-SNTA1 can cause gain-of-function of Na(v)1.5 similar to the LQT3. PMID: 19684871
    14. Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. PMID: 20009079

    顯示更多

    收起更多

  • 相關疾病：
    Long QT syndrome 12 (LQT12)
  • 亞細胞定位：
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Syntrophin family
  • 組織特異性：
    High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
  • 數據庫鏈接：

    HGNC: 11167

    OMIM: 601017

    KEGG: hsa:6640

    STRING: 9606.ENSP00000217381

    UniGene: Hs.31121



主站蜘蛛池模板： 日韩视频在线观看| 在线精品视频一区二区三区| 无码人妻少妇伦在线电影| 无尺码精品产品视频| 在线播放人成视频观看| 国产亚洲精品一区二三区| 色偷偷偷在线视频播放| 色欲人妻aaaaaaa无码| 天堂网www天堂在线资源| 国产精品av一区二区三区不卡蜜| 婷婷色香五月综合激激情 | 男女性杂交内射妇女bbwxz| 午夜av亚洲一码二中文字幕青青| 99久久99视频只有精品| 又大又硬又爽免费视频| 国精品无码一区二区三区在线蜜臀| 免费看无码自慰一区二区| 久久精品亚洲综合专区 | 黄网站色视频免费国产| 久久亚洲欧美国产精品| 亚洲丁香五月天缴情综合| 国产又粗又猛又大爽老大爷| 久久青青草原国产最新片完整| 欧美人与动性xxxxx交性| 亚洲 高清 成人 动漫| 亚洲中文字幕精品久久| 亚洲国产av无码综合原创国产| 免费观看的av毛片的网站| 国产成a人亚洲精品无码樱花| 看成年全黄大色黄大片| 国产 | 欧洲野花视频天堂视频p| 少妇人妻精品一区二区三区| 特黄特级毛片免费视频| 国产sm精品调教视频网址 | 性欧美性另类巨大| 国内精品自线一区二区三区2021| 在线欧美中文字幕农村电影| 久久se精品一区精品二区 | 大尺度无遮挡激烈床震网站| www国产亚洲精品| 真人做受试看120分钟小视频|