在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SNIP1 Antibody

  • 中文名稱:
    SNIP1兔多克隆抗體
  • 貨號:
    CSB-PA021931GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FHA domain containing protein SNIP1 antibody; FHA domain-containing protein SNIP1 antibody; FLJ12553 antibody; PMRED antibody; Smad nuclear interacting protein (Smad nuclear interacting) antibody; smad nuclear interacting protein 1 antibody; Smad nuclear interacting protein antibody; Smad nuclear-interacting protein 1 antibody; SNIP1 (Smad nuclear interacting protein) antibody; SNIP1 antibody; SNIP1_HUMAN antibody; Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75) antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SNIP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
  • 基因功能參考文獻:
    1. these data demonstrated a novel mechanism whereby SNIP1 regulates intestinal inflammation through modulating intestinal epithelial barrier function PMID: 29426045
    2. SUMOylation of SNIP1 leads to the loss of SNIP1-mediated inhibition on expression of the TGF-beta target genes PAI-1 and MMP2 and eventually enhances TGF-beta-regulated cell migration and invasion. PMID: 27703003
    3. Involvement of SNIP1 in progression of lung cancer by regulating the RB/HDAC1 interaction. PMID: 23932364
    4. SNIP1 in cells strongly activated the heat shock element signaling pathway, and SNIP1 might selectively regulate the transcription of some heat shock proteins through associating with heat shock elements PMID: 22020748
    5. Study identified sequence variants in the known disease-causing genes SLC6A3 and FLVCR1, and present evidence to strongly support the pathogenicity of variants identified in TUBGCP6, BRAT1, SNIP1, CRADD, and HARS. PMID: 22279524
    6. overexpression of HIF-1alpha, TWIST2 or SNIP1 correlated with poor disease-free survival in patients with tongue squamous cell carcinoma PMID: 21167768
    7. define both a new function for SNIP1 and identify a previously unrecognized regulator of the cell cycle and cyclin D1 expression PMID: 15378006
    8. Smad-binding peptide aptamers can be developed to selectively inhibit TGF-beta-induced gene expression. PMID: 15750622
    9. SNIP1 functions as a regulator of c-Myc activity, binding the N c-Myc N terminus through its C terminus, and that SNIP1 enhances the transcriptional activity of c-Myc by stabilizing it against proteosomal degradation and bridging the c-Myc/p300 complex. PMID: 17157259
    10. SNIP1, the human homolog of DDL, is involved in miRNA biogenesis and interacts with Drosha PMID: 18632581
    11. Study shows a novel mechanism regulating Cyclin D1 expression and offers new insight into the role of SNIP1 and associated proteins as regulators of proliferation and cancer. PMID: 18794151

    顯示更多

    收起更多

  • 相關疾病:
    Psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED)
  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Ubiquitous, with highest expression in heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 30587

    OMIM: 608241

    KEGG: hsa:79753

    STRING: 9606.ENSP00000296215

    UniGene: Hs.47232



主站蜘蛛池模板: av大片在线无码永久免费| 黑人巨大精品欧美黑寡妇| 法国伦理少妇愉情| 国产成人一区二区三区别| 日韩精品一区二区三区影院| 黑人巨大videos精品| 成年无码动漫av片在线尤物网站| 精品人妻av区波多野结衣| 亚洲国产成人一区二区精品区| 精产国品一区二区三产区| 国内精品自线在拍2020不卡| 亚洲伊人成无码综合网| 国产免费毛卡片| 人妻少妇-嫩草影院| 成年女人片免费视频播放a| 奶头好大狂揉60分钟视频| 亚洲欧美一区二区三区日产| 碰超免费人妻中文字幕| 久久不见久久见免费影院视频| 欧美 日韩版国产在线播放| 精品人伦一区二区三区蜜桃免费| 精品国产乱码久久久久久夜深人妻 | 欧美 亚洲 国产 另类| 亚洲熟妇av一区二区三区宅男| 欧美伊人色综合久久天天 | 青青草国产免费久久久下载| 国产精品久久一区二区三区| 骚片av蜜桃精品一区| 不卡av中文字幕手机看 | 午夜家庭影院| 国产一区二区野外| 女人爽到高潮视频免费直播| 丰满熟妇人妻av无码区| 欧美 国产 综合 欧美 视频| 亚洲综合色婷婷六月丁香宅男大增| 成人三级视频在线观看一区二区| 欧美日韩色另类综合| 51社区精品视频| 97夜夜澡人人双人人人喊| 亚洲国产成人无码网站大全| 精品国产成人一区二区三区 |