在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SNIP1 Antibody

  • 中文名稱:
    SNIP1兔多克隆抗體
  • 貨號:
    CSB-PA021931GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FHA domain containing protein SNIP1 antibody; FHA domain-containing protein SNIP1 antibody; FLJ12553 antibody; PMRED antibody; Smad nuclear interacting protein (Smad nuclear interacting) antibody; smad nuclear interacting protein 1 antibody; Smad nuclear interacting protein antibody; Smad nuclear-interacting protein 1 antibody; SNIP1 (Smad nuclear interacting protein) antibody; SNIP1 antibody; SNIP1_HUMAN antibody; Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75) antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SNIP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
  • 基因功能參考文獻:
    1. these data demonstrated a novel mechanism whereby SNIP1 regulates intestinal inflammation through modulating intestinal epithelial barrier function PMID: 29426045
    2. SUMOylation of SNIP1 leads to the loss of SNIP1-mediated inhibition on expression of the TGF-beta target genes PAI-1 and MMP2 and eventually enhances TGF-beta-regulated cell migration and invasion. PMID: 27703003
    3. Involvement of SNIP1 in progression of lung cancer by regulating the RB/HDAC1 interaction. PMID: 23932364
    4. SNIP1 in cells strongly activated the heat shock element signaling pathway, and SNIP1 might selectively regulate the transcription of some heat shock proteins through associating with heat shock elements PMID: 22020748
    5. Study identified sequence variants in the known disease-causing genes SLC6A3 and FLVCR1, and present evidence to strongly support the pathogenicity of variants identified in TUBGCP6, BRAT1, SNIP1, CRADD, and HARS. PMID: 22279524
    6. overexpression of HIF-1alpha, TWIST2 or SNIP1 correlated with poor disease-free survival in patients with tongue squamous cell carcinoma PMID: 21167768
    7. define both a new function for SNIP1 and identify a previously unrecognized regulator of the cell cycle and cyclin D1 expression PMID: 15378006
    8. Smad-binding peptide aptamers can be developed to selectively inhibit TGF-beta-induced gene expression. PMID: 15750622
    9. SNIP1 functions as a regulator of c-Myc activity, binding the N c-Myc N terminus through its C terminus, and that SNIP1 enhances the transcriptional activity of c-Myc by stabilizing it against proteosomal degradation and bridging the c-Myc/p300 complex. PMID: 17157259
    10. SNIP1, the human homolog of DDL, is involved in miRNA biogenesis and interacts with Drosha PMID: 18632581
    11. Study shows a novel mechanism regulating Cyclin D1 expression and offers new insight into the role of SNIP1 and associated proteins as regulators of proliferation and cancer. PMID: 18794151

    顯示更多

    收起更多

  • 相關疾病:
    Psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED)
  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Ubiquitous, with highest expression in heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 30587

    OMIM: 608241

    KEGG: hsa:79753

    STRING: 9606.ENSP00000296215

    UniGene: Hs.47232



主站蜘蛛池模板: 国产免费丝袜调教视频| 免费人成无码大片在线观看| 无码成人一区二区三区| 欧美激情乱人伦| 午夜性色吃奶添下面69影院| 国产精品久久人妻无码| 久久人妻少妇嫩草av无码专区| 国产在线拍偷自揄拍无码| 天堂在/线中文在线资源 官网 | 成 人免费va视频| 少妇暴力深喉囗交3p| 国产av久久久久精东av| 特黄三级又爽又粗又大| 国产乱人激情h在线观看| 黄在线看片免费人成视频 | 亚洲综合无码一区二区| 乱人伦xxxx国语对白| 亚洲国产av无码一区二区三区| 又黄又爽又色视频| 成人性做爰片免费视频| 精产国品一区二区三产区| 撕开奶罩揉吃奶高潮av在线观看| 国产欧美成人一区二区a片| 日韩成人一区二区三区在线观看| 中文字幕久久久久人妻中出| 校花高潮抽搐冒白浆| 亚洲春色在线视频| 欧美黑人欧美精品刺激| 久拍国产在线观看| 日本一卡2卡3卡四卡精品网站| 成人做爰www网站视频| 亚洲性夜夜综合久久7777| 69国产成人精品午夜福中文| 青青草97国产精品免费观看| 99久久国语露脸精品国产色| 国产精品国产三级国av在线观看| 综合久久给合久久狠狠狠97色| aaaaa少妇高潮大片| 在线天堂资源www在线污| 欧美日韩一区二区三区在线观看视频 | 正在播放的国产a一片|