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SMNDC1 Antibody

  • 中文名稱：
    SMNDC1兔多克隆抗體
  • 貨號：
    CSB-PA021840LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA021840LA01HU at dilution of 1:100
    • Immunoprecipitating SMNDC1 in Hela whole cell lysate
      Lane 1: Rabbit control IgG (1µg) instead of CSB-PA021840LA01HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA021840LA01HU (6µg) + Hela whole cell lysate (500µg)
      Lane 3: Hela whole cell lysate (10µg)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SMNDC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SMNDC1
  • 別名：
    30 kDa splicing factor SMNrp antibody; MGC106917 antibody; MGC112663 antibody; SMN related protein antibody; SMN-related protein antibody; smndc1 antibody; SMNR antibody; SPF30 antibody; SPF30_HUMAN antibody; Splicing factor 30, survival of motor neuron-related antibody; Survival motor neuron domain containing 1 antibody; Survival motor neuron domain containing protein 1 antibody; Survival motor neuron domain-containing protein 1 antibody; Survival of motor neuron related splicing factor 30 antibody; Survival of motor neuron-related-splicing factor 30 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SMNDC1 Antibody (CSB-PA021840LA01HU)，的標記方式是Non-conjugated。對于SMNDC1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA021840LB01HU SMNDC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA021840LC01HU SMNDC1 Antibody, FITC conjugated
    Biotin CSB-PA021840LD01HU SMNDC1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in spliceosome assembly.
  • 基因功能參考文獻：
    1. The results show that SMNDC1 mRNA 5'-UTR forms an intramolecular, parallel G quadruplex structure comprised of three G quartet planes, which is bound specifically by FMRP both in vitro and in mouse brain lysates. PMID: 28612854
    2. The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively. PMID: 22363433
    3. The structures of SMN and SPF30 Tudor domains bound to symmetric and asymmetric dimethylated arginine (DMA) are presented. PMID: 22101937
    4. U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition PMID: 18211889
  • 亞細胞定位：
    Nucleus speckle. Nucleus, Cajal body.
  • 蛋白家族：
    SMN family
  • 組織特異性：
    Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
  • 數據庫鏈接：

    HGNC: 16900

    OMIM: 603519

    KEGG: hsa:10285

    STRING: 9606.ENSP00000358605

    UniGene: Hs.632093



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