在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SMAD4 Antibody

  • 中文名稱:
    SMAD4兔多克隆抗體
  • 貨號:
    CSB-PA780020
  • 規格:
    ¥1100
  • 圖片:
    • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA780020(SMAD4 Antibody) at dilution 1/20. (Original magnification: ×200)
    • The image is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA780020(SMAD4 Antibody) at dilution 1/20. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA780020(SMAD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human SMAD4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

相關產品

靶點詳情

  • 功能:
    In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions. Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in response to TGF-beta. May act as a tumor suppressor. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
  • 相關疾病:
    Pancreatic cancer (PNCA); Juvenile polyposis syndrome (JPS); Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome (JP/HHT); Colorectal cancer (CRC); Myhre syndrome (MYHRS)
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Dwarfin/SMAD family
  • 數據庫鏈接:

    HGNC: 6770

    OMIM: 114500

    KEGG: hsa:4089

    STRING: 9606.ENSP00000341551

    UniGene: Hs.75862



主站蜘蛛池模板: 日本va欧美va欧美va精品| 国产嘿嘿嘿视频在线观看| 欧美性性性性o00xx| 国产精品一区二区av片| 国产精品亚亚洲欧关中字幕 | 亚洲国产精品特色大片观看完整版| 又色又爽又黄的吃奶视频免费观看| 韩国精品久久久久久无码| 俄罗斯老熟妇色xxxx| 丰满少妇69激情啪啪无| 久久精品国产精品青草| 日日碰狠狠躁久久躁96| 最新国产精品无码| 久久久无码精品亚洲日韩啪啪网站| 中文字幕亚洲欧美日韩在线不卡| 国产精品久久无码一区二区三区网| 国产福利精品一区二区| 伊人久久大香线蕉av网站| 亚洲欧美综合精品二区| 内射老阿姨1区2区3区4区| 亚洲精品第一国产综合野草社区| 精品爆乳一区二区三区无码av| 日本天天黄网站| 久久综合亚洲欧美成人| 性欧美丰满熟妇xxxx性仙踪林 | 在线观看国产成人av片| 国语对白嫖老妇胖老太| 99久久人妻精品免费一区| 亚洲日本va午夜中文字幕一区| 少妇被爽到高潮动态图| 色一情一区二| 丰满人妻熟妇乱又伦精品app| 日本三级香港三级三级人!妇久| 2019nv天堂香蕉在线观看| 欧美成人看片一区二区| 日韩成人无码v清免费| 中文字幕亚洲一区二区三区| 国内精品久久久久久中文字幕| 国产成+人+综合+亚洲欧美丁香花| 欧美中文字幕无线码视频| 成 人 网 站 免费 在线|