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  4. SLITRK6 Antibody, Biotin conjugated

SLITRK6 Antibody, Biotin conjugated

  • 中文名稱：
    SLITRK6兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA867155LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLITRK6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    4832410J21Rik antibody; DFNMYP antibody; MGC119595 antibody; MGC119596 antibody; MGC119597 antibody; OTTHUMP00000066012 antibody; SLIK6_HUMAN antibody; SLIT and NTRK like family member 6 antibody; SLIT and NTRK like protein 6 antibody; SLIT and NTRK-like protein 6 antibody; Slit and trk like 6 antibody; Slit and trk like gene 6 antibody; SLITRK 6 antibody; Slitrk6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulator of neurite outgrowth required for normal hearing and vision.
  • 基因功能參考文獻(xiàn)：
    1. Analysis of two exons of SLITRK6 gene in a Moroccan family identify a novel single deleterious mutation c.696delG, p.Trp232Cysfs*10 at homozygous state in the exon 2 of the SLITRK6, a gene reported to cause deafness and myopia in various populations. PMID: 29551497
    2. Human cytomegalovirus downregulates SLITRK6 expression through IE2. PMID: 27530937
    3. SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans. PMID: 23946138
    4. SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness. PMID: 23543054
  • 相關(guān)疾病：
    Deafness and myopia (DFNMYP)
  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    SLITRK family
  • 組織特異性：
    In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23503

    OMIM: 221200

    KEGG: hsa:84189

    STRING: 9606.ENSP00000383143

    UniGene: Hs.525105



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