在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC8A2 Antibody

SLC8A2 Antibody

  • 中文名稱：
    SLC8A2兔多克隆抗體
  • 貨號：
    CSB-PA244891
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA244891(SLC8A2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA244891(SLC8A2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    SLC8A2 antibody; KIAA1087 antibody; NCX2 antibody; Sodium/calcium exchanger 2 antibody; Na(+)/Ca(2+)-exchange protein 2 antibody; Solute carrier family 8 member 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Rat
  • 免疫原：
    Synthetic peptide of Human SLC8A2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion.
  • 基因功能參考文獻：
    1. Structure-Dynamic Coupling Through Ca(2+)-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Variants PMID: 29594857
    2. SLC8A2 inhibited the angiogenesis of U87MG cells, probably through combined inhibition of endothelium-dependent and endothelium-nondependent angiogenesis (vascular mimicry pattern). Totally, SLC8A2 serves as a tumor suppressor gene and inhibits invasion, angiogenesis and growth of glioblastoma PMID: 29047259
    3. NCX isoforms (NCX2, NCX3) contribute to mitochondrial Na(+)/Ca(2+) exchange in human DAergic neurons and may act downstream of PINK1 in the prevention of neurodegeneration by m[Ca(2+)] accumulation. PMID: 23224884
    4. the large cytosolic loop of NCX1, NCX2, and NCX3 is involved in acquisition of immunosuppressive drug specificity PMID: 23224887
    5. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte. PMID: 23224890
    6. Data suggest that NCX-mediated Ca(2+) fluxes normally exist in human ASM (potentially contributing to rapid Ca(2+) fluxes), and contribute to enhanced [Ca(2+)](i) regulation in airway inflammation. PMID: 21858195
    7. Results demonstrate a selective regulation of NCX1, NCX2 and NCX3 isoforms in Alzheimer's disease cortex, specifically in terminals containing amyloid-beta. PMID: 21382638
    8. The aim of this study was to investigate if NCX2 might be a tumour suppressor gene involved in glioma. Results indicate that DNA methylation may play a key role in the transcriptional silencing of NCX2. PMID: 20132488
    9. plasma membrane Na+/Ca2+ exchangers have inhibitory interactions with the 14-3-3 proteins PMID: 16679322

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, dendritic spine.
  • 蛋白家族：
    Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC8 subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11069

    OMIM: 601901

    KEGG: hsa:6543

    STRING: 9606.ENSP00000236877

    UniGene: Hs.172884



主站蜘蛛池模板： 国产尤物精品视频| 欧洲美女熟乱av| 欧美丰满熟妇xxxx性ppx人交| 欧美性大战xxxxx久久久| 久国产精品人妻aⅴ| 色欲天天天综合网| 青青草av国产精品| 88国产精品视频一区二区三区 | 两根大肉大捧一进一出好爽视频| 国产成人无码免费视频97| 天天影视性色香欲综合网| 亚洲aⅴ男人的天堂在线观看 | 国产又色又爽又黄的免费| 亚洲精品456在线播放| 秋霞午夜久久午夜精品| 大肉大捧一进一出视频| 亚洲理论在线a中文字幕| 久久高清超碰av热热久久| 天天狠天天透天干天天怕∴| 一二三四免费观看在线视频中文版| 久久人人爽人人爽人人片av| 亚洲欧美人成网站aaa| 极品美女扒开粉嫩小泬图片| 欧美老熟妇xb水多毛多| 成人麻豆日韩在无码视频| 自拍偷亚洲产在线观看| 免费无码又爽又刺激聊天app| 国产成人无码18禁午夜福利p| 18禁无遮挡无码网站免费| 久久成人网站亚洲综合| 久久久久99精品成人片三人毛片| 免费人成年激情视频在线观看| 国产亚洲综合欧美视频| 国产精品亚洲专区无码唯爱网 | 99精品国产综合久久久久五月天| 99久久久国产精品免费蜜臀| 爱色精品视频一区二区| 亚洲精品国产av现线| 超碰国产精品久久国产精品99| 久久香蕉国产线看观看怡红院妓院 | 久久青青草免费线频观|