在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC7A9 Antibody

SLC7A9 Antibody

  • 中文名稱：
    SLC7A9兔多克隆抗體
  • 貨號：
    CSB-PA146812
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA146812(SLC7A9 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA146812(SLC7A9 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC7A9
  • 別名：
    SLC7A9 antibody; BAT1b(0,+)-type amino acid transporter 1 antibody; b(0,+)AT1 antibody; Glycoprotein-associated amino acid transporter b0,+AT1 antibody; Solute carrier family 7 member 9 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SLC7A9
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.
  • 基因功能參考文獻：
    1. Study shows that various computational tools were able to distinguish cystinuria-causing mutations from benign polymorphisms. Only missense mutation V142A had a benign effect on the protein structure and function of SLC7A9. The intron variant c.604+66C>G in SLC7A9 gene probably affected the splicing process. PMID: 30069816
    2. Thirteen pediatric patients with cystine stones were evaluated in our clinic between 2012 and 2015. Gene mutations in SLC3A1 and SLC7A9 were investigated PMID: 28689648
    3. Spectrum of SLC3A1 and SLC7A9 mutations in cystinuria patients presenting with prenatal hyperechoic colon has been described. PMID: 28646536
    4. Analysis showing how different mutations in SLC3A1 and SLC7A9 affect severity of cystinuria. PMID: 28812535
    5. A new variation in exon 4 of the SLC7A9 gene was identified in cystinuria patients, which was insertion of 1 adenine nucleotide between 2 cytosine nucleotides in position c.213-214insA. PMID: 28270646
    6. Five SLC3A1 and SLC7A9 mutations appear to be responsible for the genetic basis of cystinuria in the Greek-Cypriot patients PMID: 26540609
    7. G105R but not R333W mutation found in Iranian cystinuria patients PMID: 26123750
    8. Report no association of SLC7A9 mutations with clinical course of disease in cystinuria patients. PMID: 25964309
    9. Case Report: novel mutation of SLC7A9 gene in cystinuria. PMID: 25599739
    10. We present six family members with a complex phenotypic profile of cystinuria based on mutations in SLC3A1 (type A) or SLC7A9 (type B). PMID: 24045899
    11. In SLC7A9 gene, one large genomic rearrangement and 24 sequence variants are found in cystinuria patients. PMID: 21255007
    12. Studies identified 6 different alleles in SLC3A1 and 2 in SLC7A9 accounting for a total of 25 copy number changes, 11 in SLC3A1 and 14 in SLC7A9. PMID: 19782624
    13. a decreasing expression gradient of heterodimeric rBAT-b(0,+)AT along the proximal tubule is responsible for virtually all apical cystine reabsorption PMID: 12167606
    14. in cystinuria, the detection rate for mutations in SLC7A9 in children was 25% in the SLC7A9 gene for non-type I chromosomes. PMID: 12234283
    15. The finding of SLC7A9 mutations in all three subtypes underscores the complex interactions between specific cystinuria genes and other factors influencing cystine excretion. PMID: 12371955
    16. Three novel SLC7A9 mutations were identified: two missense mutations (P261L and V330M) and one single base-pair deletion (1009 delA) PMID: 12820697
    17. deletions in SLC7A9 in cystinuria PMID: 14531788
    18. Mutations of this protein have a population-specific distribution among south-east Europeans living in Germany. PMID: 14991253
    19. Mutational analysis should focus on this gene in inheritance of cytinuria. PMID: 15635077
    20. Disease: cystinuria, type non-I.Deletion codon 50. PMID: 15818799
    21. gene deletion , codon 423 in cystinuria, type non-1. PMID: 15818803
    22. SLC3A1 and SLC7A9 mutations may have roles in cystinuria PMID: 16138908
    23. Mutations of SLC7A9 for Japanese cystinuria patients are different from those reported for European and American population. PMID: 16609684
    24. all carriers of a SLC7A9 mutation manifested cystinuria if their normal allele had non-wild type nucleotides in two or more of the identified polymorphic sites PMID: 16838140
    25. a novel splice-acceptor site mutation in the SLC7A9 gene may have a role in cystinuria [case report] PMID: 17701443
    26. To characterize the clinical features and analyze the genetic basis of cystinuria in an inbred Moslem Arab Israeli family. Sequencing of this gene revealed a missense mutation, P482L, in the homozygous state in all three affected sibs PMID: 17710781
    27. Twenty-four novel mutations in a cohort of 85 patients by direct sequencing of the SLC3A1 and SLC7A9 cystinyuria genes are reported. PMID: 18752446
    28. SLC3A1 and SLC7A9 mutations identified in 52 Greek cystinuria patients; in total 14 mutations were identified in SLC3A1 and 12 in SLC7A9. PMID: 18778962
    29. Suggest that amino acid transporters B(0)AT1 and b(0,+)AT are involved in the reabsorption of L-citrulline in the kidney, at least in part, by mediating the apical membrane transport of L-citrulline in renal tubule cells. PMID: 19322909

    顯示更多

    收起更多

  • 相關疾病：
    Cystinuria (CSNU)
  • 亞細胞定位：
    Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amino acid-polyamine-organocation (APC) superfamily
  • 組織特異性：
    Expressed in the brush border membrane in the kidney (at protein level). Kidney, small intestine, liver and placenta.
  • 數據庫鏈接：

    HGNC: 11067

    OMIM: 220100

    KEGG: hsa:11136

    STRING: 9606.ENSP00000023064

    UniGene: Hs.743345



主站蜘蛛池模板： 亚洲国色天香卡2卡3卡4| 免费无码又爽又刺激网站| 国产超碰人人爽人人做| 国产成人综合色视频精品| 亚洲精品卡一卡三卡四卡乱码| 亚洲美女被黑人巨大在线播放| 中国内地毛片免费高清| 国产精品久久久久久亚洲影视| 亚洲无日韩码精品| 亚洲成av人最新无码| 中文无码一区二区不卡αv| 免费观看的av在线播放| 亚洲日韩va在线视频| 国产无遮挡又黄又爽高潮| 熟女体下毛毛黑森林| 亚洲αv无码一区二区三区四区| 97国产在线看片免费人成视频| 天天躁日日躁狠狠躁性色avq| 国产农村妇女精品一二区| 国产精品人妻系列21p| 无码专区6080yy国产电影| 亚洲综合天堂av网站在线观看| 女人色极品影院| 久久午夜色播影院| 好男人社区www在线观看| 国产免费视频| 成人无码免费视频在线播| 在线播放国产麻豆va剧情| 性视频播放免费视频| 国产欧美va欧美va香蕉在线观看| 四虎影视88aa久久人妻| 欧美性猛少妇xxxxx免费| 一道久久爱综合久久爱| 国产亚洲成av人片在线观看| 狠狠做久久深爱婷婷| 青青草原精品99久久精品66| 国产一区二区在线视频| 97无码精品综合| 国产情侣一区二区| 欧美大浪妇猛交饥渴大叫| 高潮毛片无遮挡高清免费视频|