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SLC7A3 Antibody, Biotin conjugated

  • 中文名稱:
    SLC7A3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA855505LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC7A3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC7A3
  • 別名:
    SLC7A3 antibody; ATRC3 antibody; CAT3 antibody; Cationic amino acid transporter 3 antibody; CAT-3 antibody; CAT3 antibody; Cationic amino acid transporter y+ antibody; Solute carrier family 7 member 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Cationic amino acid transporter 3 protein (428-475AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
  • 基因功能參考文獻:
    1. rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
    2. knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
    3. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
    4. is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
    5. It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251

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  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
  • 組織特異性:
    Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
  • 數據庫鏈接:

    HGNC: 11061

    OMIM: 300443

    KEGG: hsa:84889

    STRING: 9606.ENSP00000298085

    UniGene: Hs.175220



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