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SLC6A17 Antibody

  • 中文名稱：
    SLC6A17兔多克隆抗體
  • 貨號：
    CSB-PA004745
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of rat stomach cells using NTT4 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC6A17
  • 別名：
    SLC6A17 antibody; NTT4 antibody; Sodium-dependent neutral amino acid transporter SLC6A17 antibody; Sodium-dependent neurotransmitter transporter NTT4 antibody; Solute carrier family 6 member 17 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NTT4.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent.
  • 基因功能參考文獻：
    1. Our genetic findings implicate homozygous SLC6A17 mutations in autosomal-recessive intellectual disability. PMID: 25704603
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. The substrate profile of the NTT4/XT1-dependent activity is similar to that of the closely related B(0)AT2/SBAT1 (SLC6A15), including a submillimolar apparent affinity for proline and leucine and a low millimolar apparent affinity for glutamine. PMID: 19147495
  • 相關疾病：
    Mental retardation, autosomal recessive 48 (MRT48)
  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, postsynapse. Cell junction, synapse, presynapse.
  • 蛋白家族：
    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A17 subfamily
  • 數據庫鏈接：

    HGNC: 31399

    OMIM: 610299

    KEGG: hsa:388662

    STRING: 9606.ENSP00000330199

    UniGene: Hs.128382



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