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  4. SLC5A4 Antibody, FITC conjugated

SLC5A4 Antibody, FITC conjugated

  • 中文名稱：
    SLC5A4兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA23589C0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC5A4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC5A4
  • 別名：
    SLC5A4 antibody; SAAT1 antibody; SGLT3 antibody; Solute carrier family 5 member 4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Solute carrier family 5 member 4 protein (579-633AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has electrogenic activity in response to glucose, and may function as a glucose sensor. Mediates influx of sodium ions into the cell but does not transport sugars. Also potently activated by imino sugars such as deoxynojirimycin (DNJ).
  • 基因功能參考文獻：
    1. Data suggest SGLT3 in neurons of portal vein wall plays role in sensing blood glucose level and in satiety response; dietary protein indirectly affects satiety response via up-regulation of intestinal gluconeogenesis and thus blood glucose. [REVIEW] PMID: 25200297
    2. the expression and functional role of SGLT3 in the human kidney PMID: 22766068
    3. hSGLT3 functions as a sugar sensor in vivo and mutating a single amino acid converts this sugar sensor into a sugar transporter similar to SGLT1. PMID: 20421923
    4. determination that SGLT3 is not a Na+/glucose cotransporter but instead a glucose sensor in the plasma membrane of cholinergic neurons, skeletal muscle, and other tissues PMID: 13130073
    5. substrate specificity study of imino sugars with hSGLT3; results for hSGLT3 are compared with those for alpha-glucosidases and human SGLT type 1 PMID: 17110502
    6. Suggest SGLT3 may be a possible candidate for changes in membrane potential of skeletal muscle during periods of glucose-supplemented exercise. PMID: 18198291

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sodium:solute symporter (SSF) (TC 2.A.21) family
  • 組織特異性：
    Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level). Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level). Detected in k
  • 數據庫鏈接：

    HGNC: 11039

    KEGG: hsa:6527

    STRING: 9606.ENSP00000266086

    UniGene: Hs.130101



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