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  4. SLC4A8 Antibody, Biotin conjugated

SLC4A8 Antibody, Biotin conjugated

  • 中文名稱：
    SLC4A8兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA649721LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC4A8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC4A8
  • 別名：
    Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody; Electroneutral sodium bicarbonate exchanger 1 antibody; k-NBC3 antibody; S4A8_HUMAN antibody; Slc4a8 antibody; SLC4A8 protein antibody; Solute carrier family 4 member 8 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Electroneutral sodium bicarbonate exchanger 1 protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
  • 基因功能參考文獻：
    1. This study confirmed the presence in human cDNA of mouse NDCBE-like transcripts (human NDCBE-A) and three novel transcripts NDCBE-C, NDCBE-D, and NDCBE-D'. PMID: 18577713
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Anion exchanger (TC 2.A.31) family
  • 組織特異性：
    Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed i
  • 數據庫鏈接：

    HGNC: 11034

    OMIM: 605024

    KEGG: hsa:9498

    STRING: 9606.ENSP00000405812

    UniGene: Hs.4749



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