在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC44A4 Antibody

  • 中文名稱:
    SLC44A4兔多克隆抗體
  • 貨號:
    CSB-PA681506LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunofluorescent analysis of Hela cells using CSB-PA681506LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC44A4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Choline transporter-like protein 4 protein (56-229AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,SLC44A4 Antibody (CSB-PA681506LA01HU),的標記方式是Non-conjugated。對于SLC44A4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA681506LB01HU SLC44A4 Antibody, HRP conjugated ELISA
    FITC CSB-PA681506LC01HU SLC44A4 Antibody, FITC conjugated
    Biotin CSB-PA681506LD01HU SLC44A4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury. Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis.; Has also thiamine pyrophosphate transporter activity.
  • 基因功能參考文獻:
    1. We found that rs2736428 was significantly associated with UC risk (allelic p = 0.0004), and the CT and TT genotypes of rs2736428 had a higher distribution compared with the CC genotypes (genotypic p = 0.001), suggesting that the T allele was a risk allele (odds ratio = 1.45, 95% confidence interval = 1.18-1.78). Moreover, one haplotype block that included rs2736428 was found to be strongly associated with UC risk as well PMID: 28753073
    2. Whole-exome sequencing revealed SLC44A4, which encodes the choline transport protein, as the pathogenic gene in this family. In the zebrafish model, downregulation of slc44a4 using morpholinos led to significant abnormalities in the zebrafish inner ear and lateral line neuromasts and contributed, to some extent, to disabilities in hearing and balance. PMID: 28013291
    3. These results suggest (i) apparent allelic heterogeneity in CFB and genetic heterogeneity in SLC44A4 across different ethnic groups; (ii) shared ulcerative colitis genetic etiological factors among Asians PMID: 27759029
    4. Critical genetic polymorphisms in SLC44A4, an ulcerative colitis susceptibility gene, have been identified in a genetic association study in North Indians. PMID: 26741288
    5. epigenetic mechanisms (histone modifications) play a role in determining the tissue-specific pattern of expression of the TPPT along the GI tract. PMID: 26901654
    6. The results also provide an indirect support for a membrane topology for hTPPT with 10 transmembrane domains as predicted by the TMHMM transmembrane helixes prediction program. PMID: 26828122
    7. Characterization of the SLC44A4 promoter and report the importance of both ELF3 and CREB-1 transcription factors in the maintenance of basal promoter activity in colonic epithelial cells. PMID: 25715703
    8. Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter. PMID: 24379411
    9. These results indicate that CTL4 mediates ACh synthesis in non-neuronal cell lines and presents a mechanism to target non-neuronal ACh synthesis without affecting neuronal ACh synthesis. PMID: 23651124
    10. These results suggest that eltrombopag can partially modulate some immune responses by TGFbeta(1) and sCTLA-4, but it does not induce immune tolerance by 24 weeks after treatment. PMID: 22789125

    顯示更多

    收起更多

  • 相關疾病:
    Deafness, autosomal dominant, 72 (DFNA72)
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Apical cell membrane.
  • 蛋白家族:
    CTL (choline transporter-like) family
  • 組織特異性:
    Highly expressed in colon, also detected in prostate, trachea and lung. Isoform 3 is also expressed in colon but a lower levels.
  • 數據庫鏈接:

    HGNC: 13941

    OMIM: 606107

    KEGG: hsa:80736

    STRING: 9606.ENSP00000229729

    UniGene: Hs.335355



主站蜘蛛池模板: 亚洲人成影院在线无码按摩店| 国产午夜精品一区二区三区四区| 久久久久99精品成人片直播| 亚洲精品乱码久久久久红杏| 在线偷着国产精选视频| 亚洲欧美人成电影在线观看| 色悠久久久久综合网国产| 亚洲精品成人无码中文毛片不卡| 国产精品第一国产精品| 无码一区二区三区在线观看| 国产精品高潮呻吟av久久无吗| 国产色欲色欱www在线| 免费无码成人av在线播放不卡| 欧美成人国产精品高潮| 美女黄18以下禁止观看| 在线 | 麻豆国产传媒61国产免费 视频在线+欧美十亚洲曰本 | 无遮挡1000部拍拍拍免费| 狠狠躁夜夜躁人人爽超碰97香蕉| 中国国产野外1级毛片视频| 一本aⅴ高清一区二区三区| 黄瓜视频在线观看网址| 天堂中文最新版在线官网在线| 日韩精品一区二区三区vr| 女人扒下裤让男人桶到爽| 好爽好硬好深高潮视频456| 麻豆高清免费国产一区| 免费午夜无码片在线观看影院 | 欧美牲交40_50a欧美牲交aⅴ| 波多野结衣绝顶大高潮| 天堂√最新版中文在线天堂 | 国产成人免费ā片在线观看| 男人的天堂av社区在线| 久久99精品久久久久久9蜜桃| 精人妻无码一区二区三区| 一区二区三区人妻无码| 欧美专区日韩视频人妻| 国产一区二区丝袜高跟鞋| 亚洲免费观看在线视频| 久久伊人精品波多野结衣| 尤物蜜芽国产成人精品区| 午夜视频在线瓜伦|