在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC39A7 Antibody

  • 中文名稱:
    SLC39A7兔多克隆抗體
  • 貨號:
    CSB-PA835673ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: SLC39A7 antibody at 3.59µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 51 kDa
      Observed band size: 51 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA835673ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC39A7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC39A7
  • 別名:
    SLC39A7; HKE4; RING5; Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Zinc transporter SLC39A7 protein (235-380AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+).
  • 基因功能參考文獻:
    1. Results suggest that solute carrier family 39 (zinc transporter), member 7 (SLC39A7) plays a crucial role in the proliferation and survival of colorectal cancer cells, which associates with colorectal tumorigenesis. PMID: 28981607
    2. These data reveal the role of ZIP7-mediated zinc release from intracellular stores in driving major pathways, such as MAPK, mTOR and PI3K-AKT, involved in providing cell survival and proliferation and often over activated in cancer. PMID: 28205653
    3. The recurrent seizures plus normal diet group showed worse performances in neurological reflex tests and reduced latencies to myoclonic seizures induced by penicillin compared with the control, which was concomitant with altered expressions of ZnT-7, MT-1, MT-2, and ZIP7. PMID: 27147436
    4. Knock-down of ZIP6 but not ZIP7 in MIN6 beta cells impaired the protective effects of GLP-1 on fatty acid-induced cell apoptosis, possibly via reduced activation of the p-ERK pathway PMID: 25969539
    5. The connection with proliferation and migration, as well as the activation of ZIP7 by CK2, a kinase that is antiapoptotic and promotes cell division PMID: 22317921
    6. Structure-function analysis of HKE4, a zinc transporter. PMID: 14525538
    7. ZIP7 is a functional zinc transporter that acts by transporting zinc from the Golgi apparatus to the cytoplasm of the cell PMID: 15705588
    8. ZIP7 is a critical component in the redistribution of zinc from intracellular stores to the cytoplasm and, as such, is essential for the zinc-induced inhibition of phosphatases, which leads to activation of growth factor receptors in MCF-7 cells PMID: 18583420
    9. ZIP7 releases zinc from the endoplasmic reticulum and might be required for tyrosine kinase activation. PMID: 19246244

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
  • 蛋白家族:
    ZIP transporter (TC 2.A.5) family, KE4/Catsup subfamily
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 4927

    OMIM: 601416

    KEGG: hsa:7922

    STRING: 9606.ENSP00000363807

    UniGene: Hs.631995



主站蜘蛛池模板: 尹人香蕉久久99天天拍久女久| 国产成人8x人网站视频| 日本少妇浓毛bbwbbwbbw| 无人去码一码二码三码区| 国产日韩av免费无码一区二区三区 | 日本xxxx丰满老妇| 军人粗大的内捧猛烈进出视频| 搡老熟女老女人一区二区| 无码人妻丰满熟妇啪啪7774| 色播在线精品一区二区三区四区| 久久ww精品w免费人成| 免费国偷自产拍精品视频| 又黄又爽又无遮挡免费的网站| 中文无码字幕中文有码字幕| 亚洲国产精品自在拍在线播放蜜臀 | 国产精品老熟女露脸视频| 亚洲开心婷婷中文字幕| 一道本在线伊人蕉无码| 美女高潮黄又色高清视频免费| www国产亚洲精品久久| 亚洲色播永久网址大全| 中文字幕亚洲综合久久菠萝蜜| 国产精品无码无需播放器| 国产白丝精品爽爽久久蜜臀| 无码熟熟妇丰满人妻porn| 中文字幕无码免费久久| 久久综合九色综合欧美狠狠| 国精品99久9在线 | 免费| 日韩中文无码有码免费视频| 非洲黑人最猛性xxxx交| 欧美va免费高清在线观看| 夜夜躁狠狠躁日日躁2022| 欧美性猛交ⅹxxx乱大交妖精| 国产无遮挡无码视频免费软件| 果冻传媒mv免费播放在线观看| 2019一級特黃色毛片免費看| 美女脱了内裤张开腿让男人桶网站| 真人性生交免费视频| 亚洲色欲av无码成人专区| 亚洲成熟丰满熟妇高潮xxxxx| 人妻少妇偷人精品无码|