在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC38A9 Antibody

SLC38A9 Antibody

  • 中文名稱：
    SLC38A9兔多克隆抗體
  • 貨號：
    CSB-PA836713LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Jurkat whole cell lysate
      All lanes: SLC38A9 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 64, 53, 57 kDa
      Observed band size: 64 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA836713LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA836713LA01HU at dilution of 1:100
    • Immunofluorescent analysis of U251 cells using CSB-PA836713LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLC38A9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ46104 antibody; FLJ90709 antibody; Homo sapiens solute carrier family 38; member 9 antibody; MGC120544 antibody; OTTHUMP00000161835 antibody; Putative sodium coupled neutral amino acid transporter 9 antibody; Putative sodium-coupled neutral amino acid transporter 9 antibody; Putative uncharacterized protein FLJ90709 antibody; S38A9_HUMAN antibody; SLC38A9 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SLC38A9 Antibody (CSB-PA836713LA01HU)，的標記方式是Non-conjugated。對于SLC38A9 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA836713LB01HU SLC38A9 Antibody, HRP conjugated ELISA
    FITC CSB-PA836713LC01HU SLC38A9 Antibody, FITC conjugated
    Biotin CSB-PA836713LD01HU SLC38A9 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids. Acts as an arginine sensor. Following activation by arginine binding, mediates transport of leucine, tyrosine and phenylalanine with high efficiency, and is required for the efficient utilization of these amino acids after lysosomal protein degradation.
  • 基因功能參考文獻：
    1. Ragulator and SLC38A9 act on the Rag GTPases to activate the mTORC1 pathway in response to nutrient sufficiency. PMID: 30181260
    2. Study validates that SLC38A9 is an arginine sensor for the mTORC1 pathway, and we uncover an unexpectedly central role for SLC38A9 in amino acid homeostasis. SLC38A9 mediates the transport, in an arginine-regulated fashion, of many essential amino acids out of lysosomes, including leucine, which mTORC1 senses through the cytosolic Sestrin proteins. PMID: 29053970
    3. Data suggest that amino acid transporter SLC38A9 controls mTORC1 activity through binding to the Rag-Ragulator complex at the lysosome upon amino acid availability. PMID: 25963655
    4. SLC38A9 is a physical and functional component of the amino acid sensing machinery that controls the activation of mTOR PMID: 25561175
    5. SLC38A9 functions upstream of the Rag GTPases and is an excellent candidate for being an arginine sensor for the mTORC1 pathway. PMID: 25567906
    6. SNPs within SLC38A9 are correlated with inflammatory bowel disease patients' 6-thioguanine nucleotide blood concentrations. PMID: 24762746

    顯示更多

    收起更多

  • 亞細胞定位：
    Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amino acid/polyamine transporter 2 family, SLC38A9 subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26907

    OMIM: 616203

    KEGG: hsa:153129

    STRING: 9606.ENSP00000316596

    UniGene: Hs.742101



主站蜘蛛池模板： 亚洲 欧美 变态 另类 综合 | 怡红院免费的全部视频| 尤物国产在线精品福利三区| 少妇人妻陈艳和黑人教练| 中文字幕亚洲综合久久蜜桃| 亚洲乱码国产乱码精品精| 国内最真实的xxxx人伦| 国产精品无码无卡无需播放器| 丰满少妇大叫太大太粗| 影视先锋男人无码在线| 天美传媒一区二区| 久久亚洲一区二区三区四区五区 | 欧美成人一区二区三区在线视频| 亚洲精品欧美综合一区二区| 西西人体www44rt大胆高清 | 久久人人妻人人做人人爽| 天天躁日日躁狠狠久久| 东京一本一道一二三区| 国产精品又黄又爽又色无遮挡| 国产日韩精品一区二区三区在线| 一二三四视频社区3在线高清| 国产成人综合亚洲看片| 亚洲精品中文字幕乱码| 精品人妻无码一区二区三区抖音| 粗大的内捧猛烈进出少妇视频| 亚洲欧洲成人a∨在线| 亚洲欧洲自拍拍偷午夜色| 精品国产成人一区二区三区 | 99国产欧美另娄久久久精品| 欧美黑人疯狂性受xxxxx喷水| 高清粉嫩无套内谢国语播放| 国产精品va在线观看老妇女| 成人丝袜激情一区二区| (无码视频)在线观看| 日本欧美一区二区三区在线播放| 久久久久国产精品人妻aⅴ果冻 | 国产乱理伦片在线观看| 老司机午夜福利视频| 日本午夜看x费免| 一个人看的免费高清www视频| 日韩无码电影|