SLC35B4 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SLC35B4 Polyclonal antibody
Uniprot No.：

Q969S0
基因名：

SLC35B4
別名：

SLC35B4 antibody; YEA4 antibody; PSEC0055 antibody; UDP-xylose and UDP-N-acetylglucosamine transporter antibody; Solute carrier family 35 member B4 antibody; YEA4 homolog antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter protein (174-200AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
基因功能參考文獻：
1. Glucose levels activate SLC35B4 expression. This triggers a downstream effect via Hsp60 and other proteins. We hypothesize that the downstream effect on the proteins is mediated via altering the glycosylation pattern inside liver cells PMID: 29867058
2. subcellular localization of SLC35B4 PMID: 21918738
3. Decreased SLC35B4 expression led to increased gluconeogenesis in HepG2 cells. PMID: 21507882
4. Transport capabilities for UDP-Glc and UDP-Xyl were determined with Golgi vesicles isolated from transformed cells PMID: 15911612
亞細胞定位：

Golgi apparatus membrane; Multi-pass membrane protein.
蛋白家族：

Nucleotide-sugar transporter family, SLC35B subfamily
數據庫鏈接：

HGNC: 20584

OMIM: 610923

KEGG: hsa:84912

STRING: 9606.ENSP00000367770

UniGene: Hs.490181

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