在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC35A1 Antibody

SLC35A1 Antibody

  • 中文名稱：
    SLC35A1兔多克隆抗體
  • 貨號：
    CSB-PA021583GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC35A1
  • 別名：
    CMP-SA-Tr antibody; CMP-Sia-Tr antibody; CMP-sialic acid transporter antibody; S35A1_HUMAN antibody; Slc35a1 antibody; Solute carrier family 35 member A1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SLC35A1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function. Efficient CMP-sialic acid uptake depends on the presence of free CMP inside the vesicles, suggesting the proteins functions as an antiporter. Binds both CMP-sialic acid and free CMP, but has higher affinity for free CMP.
  • 基因功能參考文獻：
    1. We performed exome sequencing on an individual with a profound neurological presentation and identified rare compound heterozygous mutations, p.Thr156Arg and p.Glu196Lys, in the CMP-sialic acid transporter, SLC35A1. Patient primary fibroblasts and serum showed a considerable decrease in the amount of N- and O-glycans terminating in sialic acid PMID: 28856833
    2. the SLC35A1 generates additional isoforms through alternative splicing. PMID: 27387429
    3. SLC35A1-deficient cells lack of alpha-dystroglycan O-mannosylation, ligand binding and incorporation of sialic acids. PMID: 25552652
    4. We confirm an autosomal recessive, generalized sialylation defect due to mutations in SLC35A1 PMID: 23873973
    5. substrate binding specificity PMID: 12682060
    6. this defect is a new type of congenital disorder of glycosylation (CDG) of type IIf affecting the transport of CMP-sialic acid into the Golgi apparatus. PMID: 15576474
    7. this study, we introduced two critical genes encoding human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter into tobacco suspension-cultured cell to pave a route for sialic biosynthetic pathway. PMID: 16343442
    8. CMP-sialic acid transporter is localized in the medial-trans Golgi PMID: 16923816

    顯示更多

    收起更多

  • 相關疾病：
    Congenital disorder of glycosylation 2F (CDG2F)
  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Nucleotide-sugar transporter family, SLC35A subfamily
  • 數據庫鏈接：

    HGNC: 11021

    OMIM: 603585

    KEGG: hsa:10559

    STRING: 9606.ENSP00000358565

    UniGene: Hs.423163



主站蜘蛛池模板： 国产真人无遮挡作爱免费视频| 任我爽橹在线精品视频| 欧美自拍另类欧美综合图片区| 久久人人爽爽爽人久久久| 天天综合天天爱天天做| 国产日本精品视频在线观看| 中文字幕人妻被公上司喝醉506 | 国产成人精品电影在线观看| 亚洲国产一区二区三区| av无码国产精品麻豆| 成人h无码动漫超w网站| 亚洲中文字幕久久精品无码喷水| 婷婷五月综合色视频| 国内外精品激情刺激在线| 成人无码一区二区三区网站| 亚瑟国产精品久久| 成人免费直播| 亚洲 欧美 另类 制服 日韩| 欧美乱码卡一卡二卡四卡免费| 熟女人妻视频| 国产亚洲精品久久久久久久软件| 日韩成人无码v清免费| 国产亚洲欧美日韩俺去了| 无码不卡av东京热毛片| 人人澡人摸人人添| 久久精品日日躁夜夜躁| 国产免费又色又爽粗视频| 色综合色狠狠天天综合色| 永久免费毛片在线播放| 麻花传媒mv国产免费观看视频 | 国产精品无码av一区二区三区| 最新精品国偷自产在线| 亚洲欧美精品综合在线观看| 国产免费高清69式视频在线观看| 中文字幕人乱码中文字幕| 很黄很色的动态图580期| 丝袜熟女国偷自产中文字幕亚洲| 国产精品无码一区二区三区免费 | 久久婷婷人人澡人人爽人人爱| 日本三级手机在线播放线观看| 中文字幕免费无码专区|