在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC34A3 Antibody

SLC34A3 Antibody

  • 中文名稱：
    SLC34A3兔多克隆抗體
  • 貨號：
    CSB-PA644639
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA644639(SLC34A3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC34A3
  • 別名：
    HHRH antibody; Na(+) dependent phosphate cotransporter 2C antibody; Na(+) Pi cotransporter 2C antibody; Na(+)-dependent phosphate cotransporter 2C antibody; Na(+)/Pi cotransporter 2C antibody; NaPi 2c antibody; NaPi-2c antibody; NPT2C antibody; NPT2C_HUMAN antibody; NPTIIC antibody; SLC34A3 antibody; Sodium dependent phosphate transport protein 2C antibody; Sodium inorganic phosphate cotransporter IIC antibody; Sodium phosphate cotransporter 2C antibody; Sodium phosphate transport protein 2C antibody; Sodium-dependent phosphate transport protein 2C antibody; Sodium-phosphate transport protein 2C antibody; Sodium/inorganic phosphate cotransporter IIC antibody; Sodium/inorganic phosphate cotransporter; type IIC antibody; Sodium/phosphate cotransporter 2C antibody; solute carrier family 34 (sodium phosphate) member 3 antibody; solute carrier family 34 (sodium/phosphate contransporter); member 3 antibody; solute carrier family 34 (type II sodium/phosphate contransporter); member 3 antibody; Solute carrier family 34 member 3 antibody; type IIc Na+ Pi cotransporter antibody; Type IIc Na+/Pi cotransporter antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SLC34A3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.
  • 基因功能參考文獻：
    1. genetic characteristics of 15 families with hereditary hypophosphatemia: Novel Mutations in PHEX and SLC34A3 PMID: 29505567
    2. This is the report of a patient with compound heterozygous mutations of SLC34A3 and normal skeletal features. Biallelic mutations in SLC34A3 can thus be associated with hypercalciuria not accompanied by rickets. PMID: 24924704
    3. Individuals with mutations affecting both SLC34A3 alleles had a significantly increased risk of kidney stone formation or medullary nephrocalcinosis, namely 46% compared with 6% observed in healthy family members carrying only the wild-type allele. PMID: 24700880
    4. this study reports the first cases of hereditary hypophosphatemic rickets with hypercalciuria in Africa and describes a novel causal mutation within the SLC34A3 gene PMID: 23246670
    5. A man with hereditary hypophosphataemic rickets with hypercalciuria & his 3 heterozygous children had a mutation in intron 5 of gene SLC34A3 (NM_080877.2:c[ 448 +5G>A] + [ 448 +5G>A]). PMID: 22806288
    6. Data show 101-bp deletion in intron 9 of the SLC34A3 gene. PMID: 22672866
    7. SLC34A3 mutations (exons and introns) were searched in two previously not reported hereditary hypophosphatemic rickets with hypercalciuria kindreds, which resulted in the identification of three novel mutations. PMID: 22387237
    8. these data suggest that mutations in SLC34A3 in hereditary hypophosphatemic rickets with hypercalciuria result in defective processing and stability PMID: 22159077
    9. Functionally important sites in the predicted first and fourth extracellular linkers of the type IIa Na+/Pi cotransporter (NaPi-IIa) were identified by cysteine scanning mutagenesis (Ehnes et al., 2004). PMID: 15504899
    10. NaP(i)-IIc has a key role in the regulation of phosphate homeostasis. PMID: 16358214
    11. Loss of function of the SLC34A3 protein presumably results in a primary renal tubular defect and is compatible with the hereditary hypophosphatemic rickets with hypercalciuria phenotype. PMID: 16358215
    12. Therefore, understanding the mechanisms that control the apical expression of NaPi-IIa and NaPi-IIc as well as their functional properties is critical to understanding how an organism achieves P i homeostasis. PMID: 16955105
    13. Hereditary hypophosphatemic rickets with hypercalciuria were speculated to be associated with the abnormal functions of phosphate transporter gene type IIc. PMID: 17968493
    14. A novel missense mutation in SLC34A3 causes hereditary hypophosphatemic rickets with hypercalciuria in humans. PMID: 18480181
    15. Novel mutation in the SLC34A3 gene in a patient with an unusual presentation of hereditary hypophosphatemic rickets with hypercalciuria. PMID: 19820004

    顯示更多

    收起更多

  • 相關疾病：
    Hereditary hypophosphatemic rickets with hypercalciuria (HHRH)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC34A transporter family
  • 數據庫鏈接：

    HGNC: 20305

    OMIM: 241530

    KEGG: hsa:142680

    STRING: 9606.ENSP00000355353

    UniGene: Hs.432442



主站蜘蛛池模板： 国产亚洲人成在线播放| 国产精品毛片无遮挡高清| 老熟妇仑乱视频一区二区| 中文在线а√在线天堂中文| 亚洲看片lutube在线观看| 亚洲人成无码网www动漫| 欧美精品v国产精品v日韩精品| 国产精品理论片| 国产精品久久久久久妇女| 精品av国产一二三四区| 少妇无码av无码一区| 亚洲精品久久婷婷丁香51| 亚洲日韩乱码一区二区三区四区 | 亚洲一区无码中文字幕乱码| 国产亚洲人成网站观看| 中国熟妇人妻xxxxx| 风韵丰满熟妇啪啪区老老熟妇 | 99久久免费国产精品| 中文无码人妻影音先锋| 欧美另类videosbestsex日本| 波多野结衣一区二区三区高清 | 蜜臀av性久久久久蜜臀aⅴ| 久久精品中文字幕无码| 日日做夜狠狠爱欧美黑人| 国产精品香蕉视频在线| 中文字幕亚韩| 中文字幕一区二区三区精华液| 欧美特级婬片毛多的少妇| 中文字幕日韩一区二区不卡| 欧美激情一区二区| 亚洲精品成人老司机影视| 无码骚夜夜精品| 玩弄japan白嫩少妇hd小说| 久久久精品区二区三区免费| 最新国产精品久久精品| 性高湖久久久久久久久| 亚洲国产日韩精品一区二区三区| 2020最新无码福利视频| 成人精品一区二区三区在线观看 | 在线 | 一区二区三区| 日韩国产网曝欧美第一页|