在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC30A3 Antibody, Biotin conjugated

  • 中文名稱:
    SLC30A3兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA859940LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC30A3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC30A3
  • 別名:
    SLC30A3; ZNT3; Zinc transporter 3; ZnT-3; Solute carrier family 30 member 3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Zinc transporter 3 protein (286-388AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in accumulation of zinc in synaptic vesicles.
  • 基因功能參考文獻:
    1. ZNT3 was only detected in human beta-cells, but not in mouse beta-cells. PMID: 29372370
    2. SNPs in the SLC30A3 gene and adjacent region are associated with schizophrenia in female but not male cases. PMID: 27750116
    3. There was a significant decreased in protein levels of ZnT3 in the prefrontal cortex in Major depression disorder, relative to control subjects. PMID: 27661418
    4. The level of ERK1/2 phosphorylation was significantly increased by tunicamycin treatment in control cells, not in SLC30A3 knockdown cells. The ERK1/2 pathway is thought to have an association with defensive effects of SLC30A3 on cellular stress such as ER stress. PMID: 27678294
    5. ZNT3 and ZNT8 (known to regulate insulin secretion) have opposite effects on insulin synthesis and secretion possibly by a transcriptional co-regulation since mRNA expression of ZNT3 was inversely correlated to ZNT8 and ZNT3 over-expression reduced insulin synthesis and secretion. PMID: 26867900
    6. An association was found between reduced ZnT3 in the prefrontal cortex and cognitive impairment in patients with either dementia with Lewy bodies or Parkinson's disease dementia. PMID: 25104558
    7. SNPs in SLC30A3 show a gender-specific association with schizophrenia in an East UK cohort. PMID: 23849395
    8. this study provides the first evidence of a role for zinc in depression in people with dementia. PMID: 24953873
    9. The results of this study suggested that ZnT3 protein levels are decreased in the spinal cords of sporadic ALS patients. PMID: 25284286
    10. hZnT-3 is expressed at low levels in leukocytes. PMID: 17971500
    11. Data show that ZNT3 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746
    12. SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity PMID: 19521526

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
  • 蛋白家族:
    Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
  • 數據庫鏈接:

    HGNC: 11014

    OMIM: 602878

    KEGG: hsa:7781

    STRING: 9606.ENSP00000233535

    UniGene: Hs.467981



主站蜘蛛池模板: 国产美女精品视频线播放| 久久精品人妻中文系列| 免免费国产aaaaa片| 久久人人爽人人爽人人片av不 | 国产亚洲日韩一区二区三区| 国产成人精品自在线拍| 成年女人黄小视频| 人妻体内射精一区二区三区| 久久丫精品久久丫| 久久99精品国产99久久6尤物| 国产xxxx69真实实拍| 成人无码视频在线观看大全| 神马午夜福利不卡片在线| 成人无码专区免费播放三区| 国产黄在线观看免费观看软件| 国产成年无码v片在线| 人妻 日韩 欧美 综合 制服| 亚洲男女羞羞无遮挡久久丫| 在线亚洲视频网站www色| 色六月婷婷亚洲婷婷六月| 蜜臀av999无码精品国产专区 | 久久精品国产一区二区三区不卡| 成年女人18级毛片毛片免费| 在线人人车操人人看视频| 爽爽午夜影视窝窝看片| 国产精品调教视频一区| 无限看片在线版免费视频大全 | 亚洲日韩激情无码一区| 久久久水蜜桃国产成人网站| 人妻熟女一区二区aⅴ水野朝阳| 伊人色合天天久久综合网| 国产白嫩美女在线观看| 性欧美丰满熟妇xxxx性久久久| 性色av无码中文av有码vr| 2020久久超碰国产精品最新 | 欧美成人h亚洲综合在线观看| 国产精品麻豆aⅴ人妻| 无码人妻丰满熟妇区96| 国产熟妇高潮叫床视频播放| 日本成本人片视频免费| 2021最新国产在线人成|