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  4. SLC25A10 Antibody, Biotin conjugated

SLC25A10 Antibody, Biotin conjugated

  • 中文名稱：
    SLC25A10兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA883371LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC25A10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC25A10
  • 別名：
    SLC25A10; DIC; Mitochondrial dicarboxylate carrier; Solute carrier family 25 member 10
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial dicarboxylate carrier protein (124-162AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
  • 基因功能參考文獻：
    1. study identifies novel genes associated with insulin sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin-stimulated lipogenesis under conditions when glucose transport is the rate limiting step PMID: 28570579
    2. the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress. PMID: 25797253
    3. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    4. SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    5. Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues PMID: 16027120

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  • 亞細胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性：
    Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed.
  • 數據庫鏈接：

    HGNC: 10980

    OMIM: 606794

    KEGG: hsa:1468

    STRING: 9606.ENSP00000345580

    UniGene: Hs.548187



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