在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC22A17 Antibody

SLC22A17 Antibody

  • 中文名稱：
    SLC22A17兔多克隆抗體
  • 貨號：
    CSB-PA196561
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA196561(SLC22A17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA196561(SLC22A17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human esophagus cancer tissue, Primary antibody: CSB-PA196561(SLC22A17 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC22A17
  • 別名：
    24p3 receptor antibody; 24p3R antibody; BOCT antibody; BOIT antibody; Brain type organic cation transporter antibody; Brain-type organic cation transporter antibody; hBOIT antibody; Lipocalin-2 receptor antibody; Neutrophil gelatinase associated lipocalin receptor antibody; Neutrophil gelatinase-associated lipocalin receptor antibody; NGAL receptor antibody; NgalR antibody; NGALR2 antibody; NGALR3 antibody; OTTHUMP00000082690 antibody; OTTHUMP00000082691 antibody; Potent brain type organic ion transporter antibody; S22AH_HUMAN antibody; Slc22a17 antibody; Solute carrier family 22 member 17 antibody; Solute carrier family 22 organic cation transporter member 17 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human SLC22A17
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
  • 基因功能參考文獻：
    1. Results showed the expression levels of NGAL and NGALR significantly downregulated in clear cell renal cell carcinoma samples. PMID: 30138675
    2. Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17. PMID: 26635366
    3. Lipocalin 2 might restore the health and regeneration potential of MSCs by decreasing senescence PMID: 24452457
    4. No significant difference was found in the expressions of NGALR mRNA in placenta among moderate preeclampsia group, severe preeclampsia group and control group. PMID: 22932106
    5. NGAL and NGALR expression might be served as novel prognostic factors and potential therapeutic targets in Hepatocellular carcinoma. PMID: 22728279
    6. This study suggested that NGAL and NGALR expression are frequently up-regulated in gliomas, and are closely associated with poor clinical outcome. PMID: 21184133
    7. These results suggested that SLC22A17, in cooperation with LCN2, to be involved in the acquisition of aggressive behavior among endometrial carcinoma cells. PMID: 21763306
    8. Neutrophil gelatinase-associated lipocalin receptor (NGALR) is differentially expressed in human glomerular disease and is significantly up-regulated by Il-1beta in HMC via MAPK/ERK activation. PMID: 21305251
    9. NGALR hypomethylation contributes to its expression in esophageal carcinomas and that this overexpression may play a role in the pathogenesis of esophageal carcinomas. PMID: 19047093

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Upon LCN2-binding, it is internalized.
  • 蛋白家族：
    Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
  • 組織特異性：
    Expressed in brain.
  • 數據庫鏈接：

    HGNC: 23095

    OMIM: 611461

    KEGG: hsa:51310

    STRING: 9606.ENSP00000206544

    UniGene: Hs.373498



主站蜘蛛池模板： 国产在线精品二区| 亚洲中文无码永久免| 国产精品卡一卡2卡三卡网站| 国产精品久久久久影院老司| 艳妇乳肉豪妇荡乳av无码福利| 精品亚洲一区二区三区在线播放| 欧美成人a天堂片在线观看| 伊人色综合九久久天天蜜桃| av东京热无码专区| 性欧美激情aa片在线播放| 亚洲国产成人精品福利| 国产山东熟女48嗷嗷叫| 国产又粗又硬又大爽黄老大爷视频| 99精品一区二区三区无码吞精| 老司机久久99久久精品播放免费| 亚洲国产成人久久精品99| av永久天堂一区二区三区| 国产私人尤物无码不卡| 丁香婷婷无码不卡在线| 久久久99精品成人片中文字幕 | 国产精品免费大片| 色护士极品影院| 国产白嫩护士在线播放| 欧美又黄又大又爽a片三年片| 亚洲精品国产suv| 欧美综合自拍亚洲综合图片区| 男人的天堂免费一区二区视频| 国产重口老太和小伙| 免费国精产品自偷自偷免费看| 国产综合精品久久丫| 日韩午夜理论片 中文字幕| 东京热加勒比无码少妇| 国产成人亚洲精品狼色在线| 日韩av第一页在线播放| 少妇真人直播免费视频| 99久久久无码国产精品性| 激情射精爆插热吻无码视频| 少妇极品熟妇人妻200片| 国产女人和拘做受视频免费| 漂亮人妻熟睡中被公侵犯中文版| 成人h无码动漫超w网站|