在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC18A1 Antibody

SLC18A1 Antibody

  • 中文名稱(chēng)：
    SLC18A1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA021426LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue
      All lanes: SLC18A1 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 57, 51, 53 kDa
      Observed band size: 57 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA021426LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) SLC18A1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    4832416I10Rik antibody; Adrenal chromaffin granule amine transporter, CGAT antibody; CGAT antibody; Chromaffin granule amine transporter antibody; MGC28683 antibody; MGC37299 antibody; SLC18A1 antibody; Solute carrier family 18 (vesicular monoamine), member 1 antibody; Solute carrier family 18 member 1 antibody; VAT 1 antibody; VAT1 antibody; Vesicular amine transporter 1 antibody; VMAT 1 antibody; VMAT1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Chromaffin granule amine transporter protein (66-120AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，SLC18A1 Antibody (CSB-PA021426LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SLC18A1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA021426LB01HU SLC18A1 Antibody, HRP conjugated ELISA
    FITC CSB-PA021426LC01HU SLC18A1 Antibody, FITC conjugated
    Biotin CSB-PA021426LD01HU SLC18A1 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells.
  • 基因功能參考文獻(xiàn)：
    1. SLC18A1 might complement other biomarkers currently under study in relation to programmed cell death protein 1/programmed cell death protein ligand 1 inhibition PMID: 30194079
    2. Polymorphisms within the SLC18A gene are associated with asthenozoospermia through sperm count and motility. PMID: 29602729
    3. Vmat1 polymorphisms are not associated with suicidal behavior. PMID: 29536333
    4. results contribute to the evidence indicating an association between the VMAT1 gene and structural brain alterations in depression. PMID: 28408293
    5. VMAT1 rs1390938/Thr136Ile is associated with mood, personality, and alcohol use in the general population. Subjects homozygous for the "hyperfunction" allele (AA; Ile/Ile) appear to be more resilient to these disorders. PMID: 26861143
    6. The germline deletions at SLC18A1 contributed to the development of CRC. PMID: 28968818
    7. rs2270641 SNP was associated with ASD risk only in over-dominant model. AA genotype of the rs1390938 was protective against ASD under dominant and recessive models. PMID: 28476685
    8. Genetic variants in VMAT1 contribute to the severity of alcohol withdrawal in patients of European descent. PMID: 26876819
    9. VMAT1 and VMAT2 are expressed in the majority of neuroblastomas PMID: 26338179
    10. SLC18A1 gene polymorphisms are associated with the risk of paranoid schizophrenia in Russians and Tatars. PMID: 25842846
    11. The data of this study showed that VMAT1 polymorphisms influence monoamine signaling, the functional response of emotional brain circuits and risk for psychopathology. PMID: 23337945
    12. Deletion of amino acids 307-338 in hVMAT1 isoform-b abolishes transport activity, and a 136-Thr partially reduces activity of isoform-a. PMID: 23090274
    13. we found a significant down-regulation of the gene coding for the vesicular monoamine transporter (VMAT1)in enteroendocrine cells infected with Chlamydia trachomatis PMID: 21883697
    14. Human bronchial arterial smooth muscle cells express OCT-1 and extraneuronal monoamine transporter(EMT). EMT is the predominant plasma membrane transporter for norepinephrine uptake. PMID: 12807698
    15. Greater expression of VMAT 1 in von Hippel-Lindau syndrome than multiple endocrine neoplasia type 2. Expression of VMAT 2 did not differ significantly. PMID: 16189177
    16. VMAT1Delta15 is not localized in large, dense core vesicles as the native form but in the endoplasmic reticulum. While VMAT1 can take up serotonin, VMAT1Delta15 cannot, indicating different functions for the two forms of VMAT1. PMID: 16326835
    17. Expression analysis confirmed that VMAT1 is expressed in human brain at the mRNA and protein level. Results suggest that variations in the VMAT1 gene may confer susceptibility to Bipolar Disorder in patients of European descent. PMID: 16936705
    18. Our findings support the hypothesis that anxiety-related personality traits are associated with variation in the VMAT1/SLC18A1 gene. PMID: 18249496
    19. Polymorphism in VMAT1 gene on chromosome 8p is associated with schizophrenia. PMID: 18451639

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    [Isoform 1]: Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.; [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily, Vesicular transporter family
  • 組織特異性：
    Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10934

    OMIM: 193002

    KEGG: hsa:6570

    STRING: 9606.ENSP00000276373

    UniGene: Hs.158322



主站蜘蛛池模板： 无码h黄动漫在线播放网站| 内射无码专区久久亚洲| 九月婷婷人人澡人人添人人爽| 国产午夜成人无码免费看不卡| 亚洲高清国产拍精品26u| 女人脱了内裤趴开腿让男躁| 激情内射人妻1区2区3区| 亚洲精品无码成人网站| 欧美人与动牲交免费观看网| 亚瑟国产精品久久| 国产精品无码一区二区在线| 成年轻人电影免费无码| 少妇精品视频无码专区| 人妻互换免费中文字幕| 乱中年女人伦av一区二区| 国产免费午夜福利不卡片在线| 日本免费一区二区三区| 色一情一区二区三区四区| 老司机久久精品最新免费| 天堂资源在线官网| 国产精品99精品久久免费| 香港三级韩国三级日本三级| 婷婷五月综合丁香在线| 一区二区三区无码免费看| 亚洲人成电影在线观看影院| 亚洲和欧洲一码二码区别7777| 成人网站免费高清视频在线观看| 久久天天躁狠狠躁夜夜2020一| 亚洲色成人一区二区三区小说 | 久久亚洲色www成人男男| 日本一卡二卡四卡无卡国产| 人妻大战黑人白浆狂泄| 交换交换乱杂烩系列yy| 情侣激情18内射骚话国产| 欧美成人午夜精品久久久| 男人的好看免费观看在线视频 | 日本无码欧美一区精品久久| 99re6热精品视频在线观看 | 国产av无码专区亚洲草草| 国产无套露脸在线观看| 青青青伊人色综合久久|