在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC13A3 Antibody

SLC13A3 Antibody

  • 中文名稱：
    SLC13A3兔多克隆抗體
  • 貨號：
    CSB-PA798619
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human placenta tissue, Human plasma tissue, Primary antibody: CSB-PA798619(SLC13A3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    dicarboxylate cotransporter 3 antibody; H sapiens mRNA for hepatocyte nuclear factor 4 gamma antibody; hNaDC3 antibody; Na antibody; Na(+)/dicarboxylate cotransporter 3 antibody; NaDC 3 antibody; NaDC-3 antibody; NADC3 antibody; S13A3_HUMAN antibody; SDCT 2 antibody; SDCT2 antibody; SLC13A3 antibody; Sodium dependent high affinity dicarboxylate transporter 2 antibody; Sodium dependent high affinity dicarboxylate transporter 3 antibody; Sodium-dependent high-affinity dicarboxylate transporter 2 antibody; Solute carrier family 13 (sodium dependent dicarboxylate transporter); member 3 antibody; Solute carrier family 13 member 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SLC13A3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-6 carbon atoms, including succinate, alpha-ketoglutarate and N-acetylaspartate. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
  • 基因功能參考文獻：
    1. NaDC3-related immunostaining was detected in the basolateral membrane of proximal tubules and in the basolateral membrane and/or luminal membrane of principal cells in connecting segments and collecting ducts PMID: 27053689
    2. OAT1 and NaDC3 in the basolateral membrane and OAT4 in the luminal membrane of proximal tubule cells are responsible for the avid renal secretion of N-carbamoylglutamate. PMID: 25354943
    3. In a study addressing genetic, social, and environmental contributors of chronic kidney disease with tubulointerstitial damages in Sri Lanka, SNP rs6066043 of SLC13A3 was found attributable risk of 50%. PMID: 24351856
    4. study concludes NaDC3 present at the basolateral membrane of proximal tubule cells mediates sodium-dependent glutathione (GSH) uptake; the kinetic data show that NaDC3 is a low-affinity GSH transporter PMID: 24247155
    5. The data 1) reveal alpha-ketoglutarate as a common high-affinity substrate of NaDC3, OAT1, and OAT3 PMID: 21865262
    6. The results indicate that SLC13A3 is a direct downstream target of PITX2 transcriptional regulation and that levels of PITX2 and SLC13A3 modulate responses to oxidative stress in ocular cells. PMID: 21873665
    7. NaDC3 promotes cellular senescence probably by inhibiting NAD(+)-dependent SIRT1. PMID: 20813124
    8. The narrow substrate specificity prevents interaction of drugs with dicarboxylate-like structure with hNaDC-3 and ensures sufficient support of the proximal tubule cells with alpha-ketoglutarate for anion secretion via organic anion transporter 1 or 3. PMID: 15561973
    9. We provide direct evidence of the localization of NaDC3 at the basolateral membrane of human renal proximal tubule cells and identify a di-hydrophobic amino acid motif VW as basolateral localization signal in the N-terminal cytoplasmic domain of NaDC3. PMID: 16331647

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
  • 組織特異性：
    Expression is highest in kidney. Detected in placenta, brain, liver and pancreas.
  • 數據庫鏈接：

    HGNC: 14430

    OMIM: 606411

    KEGG: hsa:64849

    STRING: 9606.ENSP00000279027

    UniGene: Hs.655498



主站蜘蛛池模板： 国产美女被遭强高潮免费网站| 午夜一区一品日本| 久久不见久久见免费影院| 日韩精品久久久久久久电影蜜臀| 亚洲大色堂人在线无码| 亚洲精品久久久久国产剧8| 免费无码毛片一区二区三区a片| 欧美日韩国产精品自在自线| 骚女人干起来舒服视频在线| 2021精品亚洲中文字幕| 亚洲一区二区三区偷拍女厕| 国产后入清纯学生妹| 欧美激情猛片xxxⅹ大3| 欧美z0zo人禽交免费观看99| 性色做爰片在线观看ww| 大肉大捧一进一出好爽动态图| 亚洲人成网线在线播放| 久久97超碰色中文字幕总站| 国产精品白浆一区二小说| 在线亚洲视频网站www色| a欧美爰片久久毛片a片| 欧美日本韩国亚洲| 久久人妻少妇嫩草av蜜桃| 国产欧美日韩另类在线专区| 久久久久国色av免费观看| 欧美激情精品久久| 久久婷婷色香五月综合缴缴情| 日本真人边吃奶边做爽免费视频 | 国产sm调教折磨视频失禁| 久久人人97超碰caoporen| 曰韩人妻无码一区二区三区综合部| 亚洲天堂2017无码中文| 99久久国产亚洲高清观看| 拍真实国产伦偷精品| 女人的精水喷出来视频| 亚洲 欧美 另类 综合 日韩 | 秋霞影院午夜伦a片欧美| 国产精品无码无卡无需播放器| 国产最新精品自产在线观看| 国产精品99久久久久久宅男| 欧美 丝袜 自拍 制服 另类|