在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLA Antibody, FITC conjugated

  • 中文名稱:
    SLA兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA613387LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLA Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLA
  • 別名:
    hSLAP antibody; SLA 1 antibody; sla antibody; SLA1 antibody; SLAP 1 antibody; SLAP antibody; SLAP-1 antibody; SLAP1 antibody; SLAP1_HUMAN antibody; Src like adapter antibody; Src like adapter protein 1 antibody; Src like adaptor antibody; SRC-like-adapter antibody; Src-like-adapter protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Src-like-adapter protein (2-276AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
  • 基因功能參考文獻:
    1. results suggest that cytoplasm-specific transduction of the SH3 and SH2 domains of SLAP has a therapeutic potential of being an immunosuppressive reagent for the treatment of various autoimmune diseases PMID: 25800872
    2. Taken together the data demonstrate that SLAP negatively regulates wild-type c-Kit signaling, but not its oncogenic counterpart, indicating a possible mechanism by which the oncogenic c-Kit bypasses the normal cellular negative feedback control PMID: 24284075
    3. upon ligand stimulation SLAP stably associates with Flt3 through multiple phosphotyrosine residues in Flt3. SLAP mRNA is differentially expressed in different cancers and its expression significantly increased in patients carrying the Flt3-ITD mutation PMID: 23300935
    4. These data provide evidence for src-like adaptor protein-dependent regulation of CD3 zeta-chain in the fine control of TCR signaling. PMID: 22798681
    5. Although SLA is a prominent glucocorticoids response gene, it does not seem to contribute to the anti-leukemic effects of glucocorticoids. PMID: 19631983
    6. The SLA molecule and its functionally relevant residues have been highly conserved throughout the evolution. PMID: 16521218

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Endosome.
  • 組織特異性:
    Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.
  • 數據庫鏈接:

    HGNC: 10902

    OMIM: 601099

    KEGG: hsa:6503

    STRING: 9606.ENSP00000394049

    UniGene: Hs.75367



主站蜘蛛池模板: 国产精品久久国产精品99| 男女午夜猛烈啪啦啦视频| 综合色就爱涩涩涩综合婷婷| 久久精品www人人爽人人| 日本肉体xxxx裸交| 久久激情日本亚洲欧洲国产中文| 国语自产视频在线| 国产裸体美女永久免费无遮挡| 激情综合色综合啪啪开心| 国产69精品久久久久久妇女迅雷| 青青草国产精品人人爱| 麻豆成人精品国产免费| 亚洲国产av无码精品无广告| 最新的国产成人精品2021| 青青草在在观免费福利线观看 | 国产精品久久久天天影视| 久久超碰97人人做人人爱| 亚洲日本乱码中文在线电影| 综合亚洲另类欧美久久成人精品| 国产精品国产三级国产a| 拍拍拍无挡免费视频| 伊人久久综合无码成人网| 精品国产一区二区三区免费| 国产肥白大熟妇bbbb视频| 国产亚洲高清国产拍精品| 亚洲精品无码精品mv在线观看| 国产偷国产偷亚洲高清app| 在线观看无码不卡av| 亚洲一区二区制服在线| 日韩人妻ol丝袜av一二区| 午夜片无码区私人影院| 最新永久无码av网址亚洲| 久久综合国产乱子伦精品免费| 无码人妻丝袜在线视频| 国产嫖妓风韵犹存对白| 欧美成人精品 一区二区三区| 中文字幕人妻丝袜二区| 国产精品久免费的黄网站| 久久综合精品国产一区二区三区无码 | 鲁鲁狠狠狠7777一区二区| 97人妻精品一区二区三区|