在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SKIV2L Antibody

  • 中文名稱:
    SKIV2L兔多克隆抗體
  • 貨號:
    CSB-PA021358GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SKIV2L
  • 別名:
    SKIV2L antibody; DDX13 antibody; SKI2W antibody; SKIV2 antibody; W antibody; Helicase SKI2W antibody; Ski2 antibody; EC 3.6.4.- antibody; Helicase-like protein antibody; HLP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SKIV2L
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).
  • 基因功能參考文獻:
    1. This meta-analysis showed that SKIV2L rs429608 was statistically associated with age-related macular degeneration(AMD) and it might exert a protective effect on AMD. Further investigations are needed to validate the association and confirm the role of SKIV2L in AMD. PMID: 27484132
    2. The present study was the first, to the best of our knowledge, to report a case of a boy with THES resulting from compound heterozygous mutations of the SKIV2L gene in China. PMID: 27431780
    3. Study reported three point mutations, which have not been previously described in other patients with THES in SKIV2L and TTC37 genes, including one nonsense, one frameshift, and one missense mutations. PMID: 27050310
    4. Data from 4 consanguineous families in Saudi Arabia suggest SKIV2L mutations in tricho-hepato-enteric syndrome can include deletions (c.3559_3579del, p.1187_1193del; 4 subjects) and nonsense mutation (c.C4102T, p.Q1368X; 1 subject). [CASE REPORT] PMID: 25714577
    5. A SKIV2L variant was associated with protection against exudative age-related macular degeneration regardless of subtypes in the Japanese population. PMID: 24865191
    6. Novel homozygous frameshift mutations in the AKR1D1 gene and in the SKIV2L gene were found in a family with severe infantile liver disease. PMID: 23679950
    7. SKIV2L is a likely causal gene for neovascular AMD, conferring a significant protective effect independent of CFH and HTRA1. PMID: 23260260
    8. The results showed that mutations in genes encoding SKIV2L cause trichohepatoenteric syndrome, establishing a link between defects of the human exosome complex and a Mendelian disease. PMID: 22444670
    9. A protective effect was observed at rs429608, an intronic SNP in SKIV2L. PMID: 20861866
    10. Our results do not support any major role of the 4 AMD-associated variants in the risk of developing PCV, but favor a predominant association with the RDBP-SKIV2L variants PMID: 19556007
    11. SKI2VL was found to be associated with the human exosome, a multiprotein complex involved in RNA degradation. PMID: 11719186

    顯示更多

    收起更多

  • 相關疾病:
    Trichohepatoenteric syndrome 2 (THES2)
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Helicase family, SKI2 subfamily
  • 數據庫鏈接:

    HGNC: 10898

    OMIM: 600478

    KEGG: hsa:6499

    STRING: 9606.ENSP00000364543

    UniGene: Hs.89864



主站蜘蛛池模板: 欧美色偷偷亚洲天堂bt| 亚洲精品高清无码视频| 国产乱人对白| 亚洲国产成人片在线观看无码 | 久久久www免费人成精品| 成人区精品一区二区不卡| 国产高清视频色拍| 无码国内精品久久综合88| 极品白嫩的小少妇| 午夜福利视频合集1000| 国产成人 综合 亚洲欧洲| 好爽好湿好硬好大免费视频| 小宝极品内射国产在线| 中文天堂国产最新| 男女又色又爽又爽视频| 色哟哟免费视频播放网站| 精品人妻av区波多野结衣 | 少妇人妻挤奶水中文视频毛片| 特级做a爰片毛片免费看| 欧美性插b在线视频网站| 人妻少妇-嫩草影院| 五月激情婷婷丁香综合基地| 婷婷色婷婷开心五月四房播播 | 欧美影视精品久久| 大肉大捧一进一出好爽视频mba| 99这里只有精品| 日韩av片无码一区二区三区 | 国产精品无码一区二区三区免费 | 99久在线国内在线播放免费观看 | 国产偷人妻精品一区| 国产在线精品一区二区三区直播| 一本清日本在线视频精品| 久久婷婷香蕉热狠狠综合| 亚洲人成小说网站色在线| 亚洲国产av天码精品果冻传媒| 亚洲国产码专区| 国产999精品成人网站| 国内大量揄拍人妻在线视频| 美女扒开腿让男人桶爽app免费看| 夜夜躁狠狠躁日日躁视频| 中文字幕aⅴ人妻一区二区|