在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SHCBP1 Antibody

SHCBP1 Antibody

  • 中文名稱：
    SHCBP1兔多克隆抗體
  • 貨號：
    CSB-PA021258GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SHCBP1
  • 別名：
    FLJ22009 antibody; PAL antibody; Protein expressed in Activated Lymphocytes antibody; SHC binding and spindle associated 1 antibody; SHC SH2 domain-binding protein 1 antibody; SHCBP_HUMAN antibody; Shcbp1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Human SHCBP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.
  • 基因功能參考文獻：
    1. SHCBP1 was found highly expressed in SS cell lines and tissues, which was linked to the poor clinical prognosis and was implicated in SS aggressive progression. SHCBP1 regulated invasion and metastasis by modulating the TGF-beta1/Smad signaling pathway and promoting the EMT in SS. PMID: 29020987
    2. Data indicate that the oncogene SS18-SSX1 promotes tumorigenesis by increasing the expression of SHC SH2-domain binding protein 1 (SHCBP1), which normally acts as a tumor promoting factor. PMID: 27572315
    3. Immunohistochemical analysis revealed SHCBP1 was significantly up-regulated in breast cancer tissues compared with adjacent normal tissues (82 of 128, 64%). Over-expressed SHCBP1 was correlated with advanced clinical stage and poorer survival. Ablation of SHCBP1 inhibited the proliferation in vitro. PMID: 27129942
    4. This study gives novel insight into the role of SHCBP in cytokinesis completion. PMID: 25486361
    5. Knockdown of SHCBP1 induced cell cycle delay. PMID: 24289556
    6. The central region of SHCBP1 was found to bind to measles virus C protein, as well as the phosphoprotein, but the two viral proteins did not compete for SHCBP1 binding. PMID: 23804634

    顯示更多

    收起更多

  • 亞細胞定位：
    Midbody. Cytoplasm, cytoskeleton, spindle.
  • 數據庫鏈接：

    HGNC: 29547

    OMIM: 611027

    KEGG: hsa:79801

    STRING: 9606.ENSP00000306473

    UniGene: Hs.123253



主站蜘蛛池模板： 亚洲国产精品一区二区久久| 免费国产va在线观看中文字| 亚洲人精品亚洲人成在线| 亚洲成av人片在线播放无码| 亚洲一区二区三区四区五区六| 国産精品久久久久久久| 亚洲午夜无码久久久久| 国产又色又爽又黄好看的视频| 国产成人国拍亚洲精品| 亚洲午夜久久久无码精品网红a片 国产亚洲日韩一区二区三区 | 亚洲国产精品无码久久久蜜芽| 亚洲精品久久久av无码专区| 国产疯狂伦交大片| 少妇高潮喷水久久久影院| 日本高清视频色wwwwww色| 天堂aⅴ无码一区二区三区| 国产午夜福利院757视频| 亚洲高清乱码午夜电影网制服| 国产偷国产偷亚州清高app | 99久久无码私人网站| 妺妺跟我一起洗澡没忍住| 一色屋精品视频在线观看免费| 一区二区三区国产精华液| 国产亚洲精品精品国产亚洲综合| 欧洲熟妇色xxxx欧美老妇| 中文字幕v亚洲日本在线| 国产精品vr虚拟专区| 人妻 校园 激情 另类| 精品国产乱码久久久久久1区2区| 久久综合九色综合97网| 18禁无遮挡肉动漫在线播放观看 | 精品国产乱码久久久久夜深人妻| 国产精品性夜天天拍拍2021| 999久久久精品国产消防器材| 国产无遮挡a片无码免费软件| 中文字幕人妻无码视频| 在线观看欧美一区二区三区| 国内精品久久久久精免费| 国产欧美在线亚洲一区| 欧美三级午夜理伦三级| 边添小泬边狠狠躁视频 |